Measuring single cell responses to the universe of chemicals (drugs, natural products,
environmental toxicants etc.) is of paramount importance to human health as phenotypic …

3D cell cultures are being utilized for drug discovery and development. However, there are
still challenges to implementing them generally in quantitative high-throughput screening …

Numerous intracellular bacterial pathogens interfere with macrophage function, including
macrophage polarization, to establish a niche and persist. However, the spatiotemporal …

Imaging flow cytometry (IFC) is a powerful screening technique that combines the
advantages of flow cytometry and optical microscopy (Basiji et al., 2007; Rees et al., 2022) …

In vitro systems mimicking brain regions, brain organoids, are revolutionizing the
neuroscience field. However, characterization of their electrical activity has remained a …

Imaging pathogens within 3D environment of biological tissues provides spatial information
about their localization and interactions with the host. Technological advances in …

Rapid and high-accuracy histological analysis is a challenging yet appealing medical
pursuit. Recent advances in biomedical imaging technologies enable rapid and high …

It is known that the organization of microtubule (MT) networks in cells is orchestrated by
subcellular structures named MT organizing centers (MTOCs). In this work, we use Light …

Reconstituted cytoskeleton composites have emerged as a valuable model system for
studying non equilibrium soft matter. Faithful capture of the dynamics of these three …

Reconstituted cytoskeleton composites have emerged as a valuable model system for
studying non-equilibrium soft matter. The faithful capture of the dynamics of these 3D, dense …