The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …

Integral membrane proteins (IMPs) fulfill important physiological functions by providing cell–
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …

Bicelles are an attractive membrane mimetic system because of their planar surface and
lipid composition, which resemble biological membranes. In addition, their orientation and …

► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

Membrane nanoobjects are very important tools to study biomembrane properties. Two
types are described herein: Bicelles and Nanodiscs. Bicelles are obtained by thorough …

Crystallization of membrane proteins remains a significant challenge. For proteins resistant
to the traditional approach of directly crystallizing from detergents, lipidic phase …

Roughly one-third of all proteins reside in biological membranes [1, 2]. Integral membrane
proteins (IMPs), which can only be released from the membrane by disruption of the …

Major biological processes occur at the biological membrane. One of the great challenges is
to understand the function of chemical or biological molecules inside the membrane; as well …

The use of nanotechnology in biotechnological applications has attracted tremendous
attention from researchers. Currently many nanomaterials, such as soft nanoparticles, are …

The interaction of the neuropeptide methionine-enkephalin (Menk) with bicelles was
investigated by solid-state NMR. Bicelles composed of dimyristoylphosphatidylcholine …