Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

J Xie, Y Wang, W Choi, P Jangili, Y Ge, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Immunological and toxicological considerations for the design of liposomes

CT Inglut, AJ Sorrin, T Kuruppu, S Vig, J Cicalo… - Nanomaterials, 2020 - mdpi.com
Liposomes hold great potential as gene and drug delivery vehicles due to their
biocompatibility and modular properties, coupled with the major advantage of attenuating …

Nanomaterials for photothermal and photodynamic cancer therapy

B Nasseri, E Alizadeh, F Bani, S Davaran… - Applied Physics …, 2022 - pubs.aip.org
In recent years, the role of optically sensitive nanomaterials has become powerful moieties
in therapeutic techniques and has become particularly emphasized. Currently, by the …

Liposomal formulations of photosensitizers

S Ghosh, KA Carter, JF Lovell - Biomaterials, 2019 - Elsevier
Photodynamic therapy (PDT) is a clinical ablation modality to treat cancers and other
diseases. PDT involves administration of a photosensitizer, followed by irradiation of target …

Recent advances in strategies for overcoming hypoxia in photodynamic therapy of cancer

B Pucelik, A Sułek, A Barzowska, JM Dąbrowski - Cancer Letters, 2020 - Elsevier
The selectivity of photodynamic therapy (PDT) derived from the tailored accumulation of
photosensitizing drug (photosensitizer; PS) in the tumor microenvironment (TME), and from …

Fluorescence-guided photoimmunotherapy using targeted nanotechnology and ML7710 to manage peritoneal carcinomatosis

BJ Liang, S Pang, R Perttila, CH Ma, P Srivastava… - Science …, 2023 - science.org
Fluorescence-guided intervention can bolster standard therapies by detecting and treating
microscopic tumors before lethal recurrence. Tremendous progress in photoimmunotherapy …

Nanomedicine combats drug resistance in lung cancer

X Zheng, X Song, G Zhu, D Pan, H Li, J Hu… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Nanoparticle systems for cancer phototherapy: An overview

TP Pivetta, CEA Botteon, PA Ribeiro, PD Marcato… - Nanomaterials, 2021 - mdpi.com
Photodynamic therapy (PDT) and photothermal therapy (PTT) are photo-mediated
treatments with different mechanisms of action that can be addressed for cancer treatment …

Photodynamic therapy and the biophysics of the tumor microenvironment

AJ Sorrin, M Kemal Ruhi, NA Ferlic… - Photochemistry and …, 2020 - Wiley Online Library
Targeting the tumor microenvironment (TME) provides opportunities to modulate tumor
physiology, enhance the delivery of therapeutic agents, impact immune response and …

Pleiotropic roles of ABC transporters in breast cancer

J He, E Fortunati, DX Liu, Y Li - International Journal of Molecular …, 2021 - mdpi.com
Chemotherapeutics are the mainstay treatment for metastatic breast cancers. However, the
chemotherapeutic failure caused by multidrug resistance (MDR) remains a pivotal obstacle …