The RNA binding protein SRSF1 is a master switch of gene expression and regulation in the immune system

S Paz, A Ritchie, C Mauer, M Caputi - Cytokine & growth factor reviews, 2021 - Elsevier
Serine/Arginine splicing factor 1 (SRSF1) is an RNA binding protein abundantly expressed
in most tissues. The pleiotropic functions of SRSF1 exert multiple roles in gene expression …

Challenges and promise of targeting miRNA in rheumatic diseases: A computational approach to identify miRNA association with cell types, cytokines, and disease …

FS Shaikh, RJ Siegel, A Srivastava, DA Fox… - Frontiers in …, 2024 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that alter the expression of target genes
at the post-transcriptional level, influencing diverse outcomes in metabolism, cell …

Biomarkers for diagnosis of axial spondyloarthritis, disease activity, prognosis, and prediction of response to therapy

WP Maksymowych - Frontiers in Immunology, 2019 - frontiersin.org
There exists a major unmet need for biomarkers that can identify axial spondyloarthritis
(axSpA) early after disease onset because of the availability of highly effective therapies …

Circulating miRNAs in bone health and disease

J Grillari, RE Mäkitie, R Kocijan, J Haschka… - Bone, 2021 - Elsevier
Abstract microRNAs have evolved as important regulators of multiple biological pathways
essential for bone homeostasis, and microRNA research has furthered our understanding of …

Novel immune mechanisms in hypertension and cardiovascular risk

R Nosalski, E McGinnigle, M Siedlinski… - … cardiovascular risk reports, 2017 - Springer
Abstract Purpose of Review Hypertension is a common disorder with substantial impact on
public health due to highly elevated cardiovascular risk. The mechanisms still remain …

microRNA‐96 promotes osteoblast differentiation and bone formation in ankylosing spondylitis mice through activating the Wnt signaling pathway by binding to SOST

S Ma, DD Wang, CY Ma… - Journal of cellular …, 2019 - Wiley Online Library
Ankylosing spondylitis (AS) refers to a type of arthritis manifested with chronic inflammation
of spine joints. microRNAs (MiRNAs) have been identified as new therapeutic targets for …

Could IL-17A be a novel therapeutic target in diabetic nephropathy?

C Lavoz, S Rayego-Mateos, M Orejudo… - Journal of clinical …, 2020 - mdpi.com
Chronic kidney disease has become a major medical issue in recent years due to its high
prevalence worldwide, its association with premature mortality, and its social and economic …

The circ_0021977/miR‐10b‐5p/P21 and P53 regulatory axis suppresses proliferation, migration, and invasion in colorectal cancer

C Lu, W Jiang, B Hui, D Rong, K Fu… - Journal of Cellular …, 2020 - Wiley Online Library
An in‐depth understanding of circular RNAs (circRNAs) indicates that they are abundant in
the eukaryotic transcriptome. Many circRNAs act as microRNA sponges; thus, they represent …

The relationship between serum levels of interleukin-2 and IL-8 with circulating microRNA-10b in patients with COVID-19

Z Bagheri-Hosseinabadi, H Ostad Ebrahim… - Iranian Journal of …, 2021 - iji.sums.ac.ir
Background: The role of cytokine storm in the immunopathogenesis of coronavirus disease
2019 (COVID-19) has been implicated. Objective: To determine the association of microRNA …

MicroRNA implications in the etiopathogenesis of ankylosing spondylitis

H Mohammadi, M Hemmatzadeh… - Journal of cellular …, 2018 - Wiley Online Library
Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory disease that affects
both axial and peripheral skeletons as well as soft tissues. Recent investigations offer that …