Assessment of the immune response to tumors is growing in importance as the prognostic
implications of this response are increasingly recognized, and as immunotherapies are …

Evidence indicates that lung cancer development is a complex process that involves
interactions between tumor cells, stromal fibroblasts, and immune cells. Tumor-infiltrating …

Multiple studies have described associations between infiltrating immune cells and
prognosis in cancer; however, the clinical relevance has most often been attributed to the T …

Purpose: The major value of prognostic markers in potentially curable non-small cell lung
cancer (NSCLC) should be to guide therapy after surgical resection. In this regard, the …

Solid tumors, beyond mere accumulation of cancer cells, form a complex ecosystem
consisting of normal epithelial cells, fibroblasts, blood and lymphatic vessels, structural …

In addition to malignant neoplastic cells, cancer tissues also include immune cells,
fibroblasts, and endothelial cells, including an abundant collection of growth factors …

Study objectives To provide a systematic overview of the literature investigating patient and
tumor factors that are predictive of survival for patients with non-small cell lung cancer …

The outcome of tumors results from genetic and epigenetic modifications of the transformed
cells and also from the interactions of the malignant cells with their tumor microenvironment …

A prognostic impact of immunoglobulin kappa C (IGKC) expression has been described in
cancer. We analysed the influence of B-cell and plasma cell markers, as well as IGKC …

Tumor-associated immune responses have polarized effects in regulating tumor growth.
Although a clear association has been shown between the tumor immune response and …