Olfactory sensory neurons (OSNs) are bipolar neurons, unusual because they turn over
continuously and have a multiciliated dendrite. The extensive changes in gene expression …

Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function.
To explore circRNAs systematically, we sequenced and computationally analysed human …

WASP family proteins are nucleation promoting factors that bind to and activate the Arp2/3
complex in order to stimulate nucleation of branched actin filaments. The WASP family …

Genetic variation in neuregulin and its ErbB4 receptor has been linked to schizophrenia,
although little is known about how they contribute to the disease process. Here, we have …

A todo o pessoal do laboratório de Química Orgânica, de um modo especial à Cláudia e à
Lipa, à Joana Brás, ao João, ao Leandro, à Teresa, à Sónia, à Andreia e ao Flávio, pela …

Background Cell migration is a fundamental biological process and has an important role in
the developing brain by regulating a highly specific pattern of connections between nerve …

Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however,
there is presently no way to predict response to guide treatment. The aim of this study is to …

Sensorineural hearing loss caused by the damage and degeneration of spiral ganglion
neurons (SGNs) is a common disease. So, the regeneration and directional growth of spiral …

The establishment of neuronal connectivity depends on the correct initial polarization of the
young neurons. In vivo, developing neurons sense a multitude of inputs and a great number …

Background Although many studies reported a close relationship between depression and
Alzheimer's disease (AD), the underlying pathophysiological mechanism remains unclear …