The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

The transition between epithelial and mesenchymal phenotype is emerging as a key
determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial …

Acidosis, a common characteristic of the tumor microenvironment, is associated with
alterations in metabolic preferences of cancer cells and progression of the disease. Here we …

Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal
transition (EMT) is the process in which cells lose epithelial integrity and become motile, a …

Epithelial-mesenchymal transition (EMT) is closely associated with the development of drug
resistance. Lipid metabolism plays an important role in EMT. This work was to study the …

Aerobic glycolysis, also referred to as the Warburg effect, has been regarded as the
dominant metabolic phenotype in cancer cells for a long time. More recently, it has been …

Cancer is a multifaceted global disease. Transformation of a normal to a malignant cell takes
several steps, including somatic mutations, epigenetic alterations, metabolic reprogramming …

A cytosolic iron chaperone poly (rC)-binding protein 1 (PCBP1) is a multifunctional RNA-
binding protein involving gene transcription, RNA regulation, and iron loading to ferritins …

The escalating epidemic of overweight and obesity is currently recognized as one of the
most significant health and economic concern worldwide. At the present time, over 1.9 billion …

Mitochondria in addition to be a main cellular power station, are involved in the regulation of
many physiological processes, such as generation of reactive oxygen species, metabolite …