Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

Simple Summary Colorectal cancer (CRC) is very common throughout the world. Despite an
improved outcome with the current treatment regimen, a huge number of patients relapse …

Colorectal cancer (CRC) is among the top three cancer with higher incident and mortality
rate worldwide. It is estimated that about over than 1.1 million of death and 2.2 million new …

Dendritic cells (DCs) are the key professional antigen-presenting cells which bridge innate
and adaptive immune responses, inducing the priming and differentiation of naive to effector …

Gastrointestinal tract is the second largest organ in the body that mainly functions in
nutrients and minerals intake through the intestinal barrier. Intestinal permeability maintains …

Redox imbalance is resulted from the destruction of balance between oxidants and
antioxidants. The dominant oxidants are reactive oxygen species (ROS), which are involved …

Patients with inflammatory bowel disease (IBD) have increased incidence of colorectal
cancer (CRC). IBD-associated cancer follows a well-characterized sequence of intestinal …

Ulcerative colitis (UC), an inflammatory bowel disease, is a chronic condition of a
multifaceted pathophysiology. The incidence of UC is increasing internationally. The current …

Colitis associated cancer (CAC) is the colorectal cancer (CRC) subtype that is associated
with bowel disease such as ulcerative colitis (UC). The data on role of NF‐κB signaling in …

Post-translational modifications such as ubiquitination play a key role in regulation of
inflammatory nuclear factor-κB (NF-κB) signalling. The Drosophila IκB kinase γ (IKKγ) Kenny …