Potential of curcumin and niacin-loaded targeted chitosan coated liposomes to activate autophagy in hepatocellular carcinoma cells: An in vitro evaluation in HePG2 …

NAN Hanafy, RF Sheashaa, EA Moussa… - International journal of …, 2023 - Elsevier
The objective of this study is to activate autophagy in hepatocellular carcinoma for the
enhancement of its cellular degradation. Liposomes incorporated chitosan in the core used …

Selenium deficiency promotes oxidative stress-induced mastitis via activating the NF-κB and MAPK pathways in dairy cow

Y Zhang, Y Xu, B Chen, B Zhao, X Gao - Biological Trace Element …, 2022 - Springer
Selenium (Se) is an antioxidant and immunomodulator that can participate in the control of
specific endocrine pathways. Disturbance of redox homeostasis is closely related to the …

[HTML][HTML] Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models

D He, S Fu, B Ye, H Wang, Y He, Z Li, J Li… - Journal of …, 2023 - Springer
Background Previous studies have shown a close association between an altered immune
system and Parkinson's disease (PD). Neuroinflammation inhibition may be an effective …

[HTML][HTML] GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy

W Guo, W Li, Y Su, S Liu, X Kan, X Ran… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Mastitis causes great psychological and physical pain among women. Our previous studies
found that niacin has anti-inflammatory effect, and the realization of this function depends on …

The Role and Mechanism of Metformin in Inflammatory Diseases

H Lin, H Ao, G Guo, M Liu - Journal of Inflammation Research, 2023 - Taylor & Francis
Metformin is a classical drug used to treat type 2 diabetes. With the development of research
on metformin, it has been found that metformin also has several advantages aside from its …

[HTML][HTML] Hydrogen-rich water mitigates LPS-induced chronic intestinal inflammatory response in rats via Nrf-2 and NF-κB signaling pathways

J Peng, Q He, S Li, T Liu, J Zhang - Veterinary Sciences, 2022 - mdpi.com
Simple Summary Our study provides substantial evidence that hydrogen-rich water can
prevent intestinal damage caused by LPS-induced stimulation. Intestinal injury caused by …

[HTML][HTML] Inhibiting nuclear factor erythroid 2 related factor 2-mediated autophagy in bovine mammary epithelial cells induces oxidative stress in response to …

R Chang, X Sun, H Jia, Q Xu, Z Dong, Y Tang… - Journal of Animal …, 2022 - Springer
Background In early lactation, bovine mammary epithelial cells undergo serious metabolic
challenges and oxidative stress both of which could be alleviated by activation of autophagy …

[HTML][HTML] Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model …

D Shao, W Shen, Y Miao, Z Gao, M Pan, Q Wei… - Journal of Animal …, 2023 - Springer
Background Mastitis not only deteriorates the composition or quality of milk, but also
damages the health and productivity of dairy goats. Sulforaphane (SFN) is a phytochemical …

Tanshinone IIa alleviates LPS-induced oxidative stress in dairy cow mammary epithelial cells by activating the Nrf2 signalling pathway

K Fu, Y Sun, J Wang, R Cao - Research in Veterinary Science, 2022 - Elsevier
Objective Mastitis is the most prevalent disease in dairy cows worldwide. Evidence has
emerged that oxidative stress plays a crucial role in the development of mastitis. This study …

[HTML][HTML] Astragalus polysaccharides and astragaloside IV alleviate inflammation in bovine mammary epithelial cells by regulating Wnt/β-catenin signaling pathway

J Fan, F Jia, Y Liu, X Zhou - Plos one, 2022 - journals.plos.org
The Wnt/β-catenin signaling regulates cell renewal and repair and is closely associated with
inflammation. Astragalus polysaccharides (APS) and astragaloside IV (AS-IV), which are the …