The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

The identification of protein–protein interaction sites is an essential intermediate step for
mutant design and the prediction of protein networks. In recent years a significant number of …

Background Comparing related structures and viewing the structures in the context of
sequence alignments are important tasks in protein structure-function research. While many …

ProTherm and ProNIT are two thermodynamic databases that contain experimentally
determined thermodynamic parameters of protein stability and protein–nucleic acid …

Background Since the publication of the first draft of the human genome in 2000,
bioinformatic data have been accumulating at an overwhelming pace. Currently, more than …

Predicting enzyme class from protein structure parameters is a challenging problem in
protein analysis. We developed a method to predict enzyme class that combines the …

Antarctic microbes are important agents for evolutionary adaptation and natural resource of
bioactive compounds, harboring the particular metabolic pathways to biosynthesize natural …

Allosteric regulation plays a crucial role in modulating protein functions and represents a
promising strategy in drug development, offering enhanced specificity and reduced toxicity …

In Xanthomonas axonopodis pv. citri (Xac or X. citri), the modA gene codes for a periplasmic
protein (ModA) that is capable of binding molybdate and tungstate as part of the ABC-type …

Breast cancer poses a significant global challenge, prompting researchers to explore novel
approaches for potential treatments. In this study, we investigated the binding free energy (Δ …