Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
Caspase‐8: A key protein of cross‐talk signal way in “PANoptosis” in cancer
M Jiang, L Qi, L Li, Y Wu, D Song… - International journal of …, 2021 - Wiley Online Library
Cysteinyl aspartate specific proteinase (Caspase)‐8 has long been considered a promoter
of apoptosis and part of the mechanism by which cytotoxic drugs kill cancer cells. With the …
of apoptosis and part of the mechanism by which cytotoxic drugs kill cancer cells. With the …
Crosstalk among m6A RNA methylation, hypoxia and metabolic reprogramming in TME: from immunosuppressive microenvironment to clinical application
F Zhang, H Liu, M Duan, G Wang, Z Zhang… - Journal of hematology & …, 2022 - Springer
The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …
[HTML][HTML] Recognition of necroptosis: From molecular mechanisms to detection methods
T Zhu, BW Wu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Necroptosis is a crucial modality of programmed cell death characterized by distinct
morphological and biochemical hallmarks, including cell membrane rupture, organelle …
morphological and biochemical hallmarks, including cell membrane rupture, organelle …
Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma
T Lomphithak, P Akara-Amornthum, K Murakami… - Scientific reports, 2021 - nature.com
Necroptosis, a regulated form of necrosis, has emerged as a novel therapeutic strategy that
could enhance cancer immunotherapy. However, its role in tumorigenesis is still debated …
could enhance cancer immunotherapy. However, its role in tumorigenesis is still debated …
In Vitro Anticancer Activity and Oxidative Stress Biomarkers Status Determined by Usnea barbata (L.) FH Wigg. Dry Extracts
Lichens represent an important resource for common traditional medicines due to their
numerous metabolites that can exert diverse pharmacological activities including anticancer …
numerous metabolites that can exert diverse pharmacological activities including anticancer …
Understanding necroptosis in pancreatic diseases
R He, Z Wang, S Dong, Z Chen, W Zhou - Biomolecules, 2022 - mdpi.com
Intermediate between apoptosis and necrosis, necroptosis is a regulated caspase-
independent programmed cell death that induces an inflammatory response and mediates …
independent programmed cell death that induces an inflammatory response and mediates …
Identification of a necroptosis-related gene signature as a novel prognostic biomarker of cholangiocarcinoma
L Xu, X Gao, J Xing, Z Guo - Frontiers in Immunology, 2023 - frontiersin.org
Background Cholangiocarcinoma (CHOL) is the most prevalent type of malignancy and the
second most common form of primary liver cancer, resulting in high rates of morbidity and …
second most common form of primary liver cancer, resulting in high rates of morbidity and …
[HTML][HTML] The Impact of Biliary Injury on the Recurrence of Biliary Cancer and Benign Disease after Liver Transplantation: Risk Factors and Mechanisms
Simple Summary Ischemia-reperfusion injury (IRI) is the source of significant graft
inflammation in liver transplantation. Such injuries can lead to increased recurrence of both …
inflammation in liver transplantation. Such injuries can lead to increased recurrence of both …
[HTML][HTML] Tumor microenvironment: Necroptosis switches the subtype of liver cancer while necrosis promotes tumor recurrence and progression
BH Özdemir - Exp Clin Transplant, 2022 - ectrx.org
Liver cancer is a heterogeneous group of solid tumors that include mainly epithelial tumors.
As with other solid carcinomas, tumor development results from an accumulation of genetic …
As with other solid carcinomas, tumor development results from an accumulation of genetic …