A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

The “Other” Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo‐Inositol Chemistry)

MP Thomas, SJ Mills, BVL Potter - … Chemie International Edition, 2016 - Wiley Online Library
Cell signaling via inositol phosphates, in particular via the second messenger myo‐inositol
1, 4, 5‐trisphosphate, and phosphoinositides comprises a huge field of biology. Of the nine …

Isolation, separation, and preconcentration of biologically active compounds from plant matrices by extraction techniques

V Raks, H Al-Suod, B Buszewski - Chromatographia, 2018 - Springer
Abstract Development of efficient methods for isolation and separation of biologically active
compounds remains an important challenge for researchers. Designing systems such as …

The urine metabolome of young autistic children correlates with their clinical profile severity

M Mussap, M Siracusano, A Noto, C Fattuoni… - Metabolites, 2020 - mdpi.com
Autism diagnosis is moving from the identification of common inherited genetic variants to a
systems biology approach. The aims of the study were to explore metabolic perturbations in …

A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy

OC Watkins, HEJ Yong, N Sharma… - Critical Reviews in Food …, 2022 - Taylor & Francis
Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and
endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid …

Scyllo-inositol, preclinical, and clinical data for Alzheimer's disease

K Ma, LAM Thomason, JA McLaurin - Advances in pharmacology, 2012 - Elsevier
Preclinical development of scyllo-inositol for the treatment of Alzheimer's disease (AD) has
been investigated in both in vitro and in vivo models with positive results. scyllo-Inositol …

[HTML][HTML] Anticonvulsant effect of ethanolic extract of Cyperus articulatus L. leaves on pentylenetetrazol induced seizure in mice

O Herrera-Calderon, R Santiváñez-Acosta… - Journal of traditional and …, 2018 - Elsevier
Cyperus articulatus (CA) rhizomes have demonstrated different properties on nervous
system. However, the leaves still have not studied to treat epilepsy. The aim of this study was …

Genome‐wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study

S Pedersen, M Kverneland, KO Nakken, K Rudi… - …, 2022 - Wiley Online Library
Objective The aim of this study was to investigate the impact of the modified ketogenic diet
on DNA methylation in adults with epilepsy. Methods In this prospective study, we …

Tipping the scales: Lessons from simple model systems on inositol imbalance in neurological disorders

AD Frej, GP Otto, RSB Williams - European journal of cell biology, 2017 - Elsevier
Inositol and inositol-containing compounds have signalling and regulatory roles in many
cellular processes, suggesting that inositol imbalance may lead to wide-ranging changes in …

[PDF][PDF] Plants and plant products with potential anticonvulsant activity–a review

S Kumar, R Madaan, G Bansal… - Pharmacognosy …, 2012 - scholar.archive.org
Epilepsy is a chronic and often progressive disorder characterized by the occurrence of
epileptic seizures, affecting about 50 million people worldwide. The prescribed synthetic …