Plasmodium parasites have a complex life cycle that includes development in the human
host as well as the Anopheles vector. Successful transmission of the parasite between its …

Onward transmission of Plasmodium falciparum from humans to mosquitoes is dependent
upon a specialised transmission stage called the gametocyte. Despite its critical role in …

Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used
for the evaluation of anti-malarial compounds. Here, to screen for anti-malarial drugs …

In the fight against malaria, transmission blocking interventions (TBIs) such as transmission
blocking vaccines or drugs, are promising approaches to complement conventional tools …

Novel antimalarial compounds targeting both the pathogenic and transmissible stages of the
human malaria parasite, Plasmodium falciparum, would greatly benefit malaria elimination …

Several regions of the world frequently use the species Moringa oleifera Lam.(Moringaceae)
in traditional medicine. This situation is even more common in African countries. Many …

Malaria elimination requires interventions able to target both the asexual blood stage (ABS)
parasites and transmissible gametocyte stages of Plasmodium falciparum. Lead antimalarial …

Despite concern that climate change could increase the human risk to malaria in certain
areas, the temperature dependency of malaria transmission is poorly characterized. Here …

Sexual reproduction in malaria parasites is essential for their transmission to mosquitoes
and offers a divergent eukaryote model to understand the evolution of sex. Through a panel …

Phenotypic cell-based screens are critical tools for discovering candidate drugs for
development, yet identification of the cellular target and mode of action of a candidate drug …