miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response

P Biswal, A Lalruatfela, SK Behera, S Biswal… - IUBMB …, 2024 - Wiley Online Library
MicroRNAs (miRNAs) are a class of noncoding RNAs of about 19–25 nucleotides, which
serve as critical modulators of various cellular and biological processes by target gene …

Regulation of the key epithelial cancer suppressor miR-124 function by competing endogenous RNAs

EA Braga, MV Fridman, AM Burdennyy… - International journal of …, 2022 - mdpi.com
A decrease in the miR-124 expression was observed in various epithelial cancers. Like a
classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins …

MiR-495–3p attenuates cell pyroptosis and endometritis through inhibiting the activation of NLRP3 inflammasome in bovine

Z Wu, G Deng, X Ma, T Zhang, S Guo, Q Zhou… - Molecular …, 2023 - Elsevier
Abstract miR-495 is aberrantly expressed and affects the progression of inflammation in
various diseases. However, the mechanisms of miR-495 in bovine endometritis remain …

Unveiling the epigenomic mechanisms of acquired platinum‐resistance in high‐grade serous ovarian cancer

R Silva, K Glennon, M Metoudi, B Moran… - … Journal of Cancer, 2023 - Wiley Online Library
Resistance to platinum‐based chemotherapy is the major cause of death from high‐grade
serous ovarian cancer (HGSOC). We hypothesise that detection of specific DNA methylation …

Role of microRNAs in cancer development and treatment

N Mehterov - International Journal of Molecular Sciences, 2023 - mdpi.com
MicroRNAs (miRNAs) represent a prominent part of the non-coding landscape of the human
genome [1]. Their role is performed on a post-transcriptional level and is accomplished by …

Dysregulation of lncRNA–miRNA–mRNA interactome as a marker of metastatic process in ovarian cancer

IV Pronina, LA Uroshlev, AA Moskovtsev… - Biomedicines, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the
female reproductive system. This pathology is asymptomatic until advanced stages and has …

[HTML][HTML] Reduced Levels of miR-145-3p Drive Cell Cycle Progression in Advanced High-Grade Serous Ovarian Cancer

E González-Cantó, M Monteiro, C Aghababyan… - Cells, 2024 - mdpi.com
High-grade serous ovarian cancer (HGSOC) is the most lethal form of gynecologic cancer,
with limited treatment options and a poor prognosis. Epigenetic factors, such as microRNAs …

Investigating the Expression of miR 203a 3p and Its Role in Inflammatory Response in Severe Preeclampsia of Iraqi women Patients–A Comparative Study

SQ Jaber, AS Kadhim, AI Al Kateeb - … and Biotechnology Research …, 2024 - journals.lww.com
Background: Preeclampsia (PE) has long been a feared condition impacting women and
their pregnancies. Researchers have recently discovered the role of miR203a-p3 in various …

Hypermethylation of long non-coding RNA genes group in the breast cancer development and progression

AD Selezneva, EA Filippova, AD Selezneva… - Bulletin of experimental …, 2022 - Springer
We analyzed changes in the level of methylation of CpG islands in four long non-coding
RNA (lncRNA) genes MEG3, ZNF667-AS1, GAS5, and SEMA3B-AS1 as promising markers …

Current data and future perspectives on DNA methylation in ovarian cancer

M Fu, F Deng, J Chen, L Fu, J Lei… - International …, 2024 - spandidos-publications.com
Ovarian cancer (OC) represents the most prevalent malignancy of the female reproductive
system. Its distinguishing features include a high aggressiveness, substantial morbidity and …