[HTML][HTML] Autoimmune hepatitis, one disease with many faces: etiopathogenetic, clinico-laboratory and histological characteristics

NK Gatselis, K Zachou, GK Koukoulis… - World journal of …, 2015 - ncbi.nlm.nih.gov
Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology
characterized by hypergammaglobulinemia, autoantibodies detection and interface …

autoimmune hepatitis–current management and challenges

K Zachou, P Muratori, GK Koukoulis… - Alimentary …, 2013 - Wiley Online Library
Background Autoimmune hepatitis (AIH) is a disease of unknown aetiology characterised by
interface hepatitis, hypergammaglobulinaemia, circulating autoantibodies and a favourable …

[图书][B] Hepatology Principles and Practice: History· Morphology Biochemistry· Diagnostics Clinic· Therapy

E Kuntz - 2006 - Springer
Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

Autoantibodies and autoantigens in autoimmune hepatitis: important tools in clinical practice and to study pathogenesis of the disease

K Zachou, E Rigopoulou, GN Dalekos - Journal of autoimmune diseases, 2004 - Springer
Autoimmune hepatitis (AIH) is a chronic necroinflammatory disease of the liver characterized
by hypergammaglobulinemia, characteristic autoantibodies, association with HLA DR3 or …

Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis

EI Rigopoulou, ET Davies, A Pares, K Zachou… - Gut, 2005 - gut.bmj.com
Background: Antinuclear antibodies (ANA) giving a rim-like/membranous (RL/M) or a
multiple nuclear dot (MND) pattern are highly specific for primary biliary cirrhosis (PBC). Aim …

Autoantibody-negative autoimmune hepatitis

AJ Czaja - Digestive diseases and sciences, 2012 - Springer
Autoimmune hepatitis has a variable clinical phenotype, and the absence of conventional
autoantibodies does not preclude its diagnosis or need for treatment. The goals of this …

T cell immunity in autoimmune hepatitis

Y Ichiki, CA Aoki, CL Bowlus, S Shimoda… - Autoimmunity …, 2005 - Elsevier
T cells play a central role in the immunopathogenesis of AIH. Until recently CD4+ T cells
were thought to be critical for disease development, increasing evidence has shown that …

Comparison of simplified score with the revised original score for the diagnosis of autoimmune hepatitis: a new or a complementary diagnostic score?

NK Gatselis, K Zachou, P Papamichalis… - Digestive and liver …, 2010 - Elsevier
BACKGROUND AND AIMS: The International Autoimmune Hepatitis Group developed a
simplified score for autoimmune hepatitis. We assessed this “new scoring system” and …

Alpha-actinin: a multidisciplinary protein with important role in B-cell driven autoimmunity

KG Oikonomou, K Zachou, GN Dalekos - Autoimmunity reviews, 2011 - Elsevier
Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the
superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple …

[HTML][HTML] Impact of genetic and environmental factors on autoimmune hepatitis

K Zachou, P Arvaniti, A Lyberopoulou… - Journal of Translational …, 2021 - Elsevier
Autoimmune hepatitis (AIH) is a chronic non-resolving liver disease characterized by diffuse
hypergammaglobulinemia, the presence of autoantibodies and characteristic histological …