[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
Current perspectives on the mechanism of action of artemisinins
J Golenser, JH Waknine, M Krugliak, NH Hunt… - International journal for …, 2006 - Elsevier
Artemisinin derivatives are the most recent single drugs approved and introduced for public
antimalarial treatment. Although their recommended use is for treatment of Plasmodium …
antimalarial treatment. Although their recommended use is for treatment of Plasmodium …
Electrospun nanofibers of polycaprolactone/collagen as a sustained-release drug delivery system for artemisinin
P Huo, X Han, W Zhang, J Zhang, P Kumar, B Liu - Pharmaceutics, 2021 - mdpi.com
The application of artemisinin (ART) in the treatment of malaria has been restricted to a
certain degree due to its inherent limitations, such as short half-life, poor solubility, limited …
certain degree due to its inherent limitations, such as short half-life, poor solubility, limited …
Gold (III) salen complex-catalyzed synthesis of propargylamines via a three-component coupling reaction
VKY Lo, Y Liu, MK Wong, CM Che - Organic Letters, 2006 - ACS Publications
Propargylamines have been synthesized by a gold (III) salen complex-catalyzed three-
component coupling reaction of aldehydes, amines, and alkynes in water in excellent yields …
component coupling reaction of aldehydes, amines, and alkynes in water in excellent yields …
Artemisinin triggers induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes
A major impediment to effective anti-leishmanial chemotherapy is the emergence of drug
resistance, especially to sodium antimony gluconate, the first-line treatment for …
resistance, especially to sodium antimony gluconate, the first-line treatment for …
Dried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin
MA Elfawal, MJ Towler, NG Reich… - Proceedings of the …, 2015 - National Acad Sciences
Pharmaceutical monotherapies against human malaria have proven effective, although
ephemeral, owing to the inevitable evolution of resistant parasites. Resistance to two or …
ephemeral, owing to the inevitable evolution of resistant parasites. Resistance to two or …
Leishmania treatment and prevention: Natural and synthesized drugs
AA Bekhit, E El-Agroudy, A Helmy, TM Ibrahim… - European journal of …, 2018 - Elsevier
Leishmaniasis affects over 150 million people all over the world, especially in subtropical
regions. Currently used antileishmanial synthesized drugs are associated with some …
regions. Currently used antileishmanial synthesized drugs are associated with some …
Dried Whole Plant Artemisia annua as an Antimalarial Therapy
Drugs are primary weapons for reducing malaria in human populations. However
emergence of resistant parasites has repeatedly curtailed the lifespan of each drug that is …
emergence of resistant parasites has repeatedly curtailed the lifespan of each drug that is …
Artemisia annua as a self-reliant treatment for malaria in developing countries
S De Ridder, F van der Kooy, R Verpoorte - Journal of ethnopharmacology, 2008 - Elsevier
Malaria is a vector-borne infectious disease caused by the protozoan Plasmodium parasites.
Each year, it causes disease in approximately 515 million people and kills between one and …
Each year, it causes disease in approximately 515 million people and kills between one and …
Artemisinins Inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense In Vitro Growth
Artemisinin compounds inhibit in vitro growth of cultured Trypanosoma cruzi and
Trypanosoma brucei rhodesiense at concentrations in the low micromolar range. Artemisinin …
Trypanosoma brucei rhodesiense at concentrations in the low micromolar range. Artemisinin …