Synthesis, molecular modeling, ADMET and fastness studies of some quinoline encompassing pyrimidine azo dye derivatives as potent antimicrobial agents

HD Trivedi, BY Patel, PK Patel, SR Sagar - Chemical Data Collections, 2022 - Elsevier
Targeting the current issue of microbial resistance and novel dye molecules for textile
industries, we have synthesized a series of novel Quinoline-Pyrimidine hybrids (3a–p). The …

[HTML][HTML] Green and Traditional One-Pot Synthesis Techniques for Bioactive Quinoline Derivatives: A Review

MC Parmar, BY Patel - Tetrahedron Green Chem, 2025 - Elsevier
The review examines one-pot strategies and their mechanistic approaches for synthesizing
the quinoline nucleus from 2009 to 2024, with a focus on their therapeutic potential. The …

Water mediated pot, atom, and step economic (PASE) synthesis of pyrimido[4,5-d]pyrimidines using ultrasound and microwave irradiation approaches

HD Trivedi, VB Joshi, BY Patel - Synthetic Communications, 2023 - Taylor & Francis
Abstract The functioning, Pot, Atom, and Step Economic (PASE) green chemistry proposition
has been approached for the synthesis of pyrimido [4, 5-d] pyrimidines by the …

Synthesis of Pyridine Clubbed Tetrahydrobenzo[b]thiophene Azo Dye Analogues Using the Gewald Reaction: Catalytic Optimization, Antibacterial, and Dye …

RV Aghara, MC Parmar, BY Patel - Russian Journal of General Chemistry, 2023 - Springer
A series of novel pyridine-bearing tetrahydrobenzo [b] thiophene-3-carbohydrazide mono
azo dyes was synthesized by combining the Gewald and azo dye approaches with basic …

A green one-pot synthetic protocol of hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one derivatives: molecular docking, ADMET, anticancer and antimicrobial studies

HD Trivedi, BY Patel, SD Hadiyal, G Italiya… - Molecular Diversity, 2024 - Springer
Abstract Ten hexahydropyrimido [4, 5-d] pyrimidine derivatives have been synthesized by
using a green and time-efficient microwave method. The synthesized motifs were evaluated …

Synthesis of 8-methyl-2-phenylquinazolin-4 (3H)-ones derived Schiff's bases: Spectroscopic properties, SAR, docking approaches and their anticancer and …

N Ramani, BY Patel, G Italiya, PS Ramalingam… - Journal of Molecular …, 2024 - Elsevier
A series of new compounds based on 8-methyl-2-phenyl quinazolinone Schiff's base were
synthesized from 3-amino quinazolinone intermediates. These compounds were evaluated …

Virtual screening of quinoline derived library for SARS-COV-2 targeting viral entry and replication

A Anju, S Chaturvedi, V Chaudhary, P Pant… - Journal of …, 2022 - Taylor & Francis
The COVID-19 pandemic infection has claimed many lives and added to the social,
economic, and psychological distress. The contagious disease has quickly spread to almost …

Synthesis, characterization and catalytic optimization of Schiff bases containing 8-methyl-quinazolinones as potent anti-inflammatory and antimicrobial scaffolds

N Ramani, I Modasiya, B Patel - Indian Journal of Chemistry (IJC), 2024 - or.niscpr.res.in
A set of twelve new quinazoline arylidene/heteroarylidene motifs were synthesized by
forming Schiff bases from the 3-amino-8-methyl-2-(p-tolyl) quinazolin-4 (3H)-one …

[HTML][HTML] Non-nucleophilic base promoted synthesis of azo-linked oxazolone-pyrazole hybrids: Antimicrobial, antitubercular, anticancer evaluations and in-silico …

BY Patel, V Joshi, S Subramanian, G Italiya… - Results in …, 2024 - Elsevier
Ten new non-nucleophilic base (DBU) catalyzed oxazolone-bearing pyrazole derivatives
were created to treat infectious diseases caused by bacterial, mycobacterial strains, and …

Domino Nitro Reduction-Friedländer Heterocyclization for the Preparation of Quinolines

K Fobi, RA Bunce - Molecules, 2022 - mdpi.com
The Friedländer synthesis offers efficient access to substituted quinolines from 2-
aminobenzaldehydes and activated ketones in the presence of a base. The disadvantage of …