Neurogenesis in stroke recovery

SH Koh, HH Park - Translational stroke research, 2017 - Springer
Stroke, resulting from limited blood flow to the brain, is one of the most important causes of
morbidity and mortality worldwide. Stroke is classified as ischemic, due to lack of blood flow …

Coenzyme Q10 and dementia: a systematic review

FJ Jiménez-Jiménez, H Alonso-Navarro… - Antioxidants, 2023 - mdpi.com
It is well known that coenzyme Q10 (CoQ10) has important antioxidant properties. Because
one of the main mechanisms involved in the pathogenesis of Alzheimer's disease (AD) and …

Interplay between mitochondrial oxidative disorders and proteostasis in Alzheimer's disease

E Llanos-González, ÁA Henares-Chavarino… - Frontiers in …, 2020 - frontiersin.org
Although the basis of Alzheimer's disease (AD) etiology remains unknown, oxidative stress
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …

Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson's disease rat model

HW Park, CG Park, M Park, SH Lee, HR Park, J Lim… - Scientific Reports, 2020 - nature.com
Parkinson's disease is a neurodegenerative disorder, and no treatment has been yet
established to prevent disease progression. Coenzyme Q10, an antioxidant, has been …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Pharmacogenomics of Alzheimer's disease: Novel therapeutic strategies for drug development

R Cacabelos, P Cacabelos, C Torrellas… - … in Drug Discovery and …, 2014 - Springer
Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …

Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model

H Baek, null Sanjay, M Park, HJ Lee - Journal of Neuroinflammation, 2023 - Springer
Abstract Cyanidin-3-O-glucoside (C3G) is a natural anthocyanin with antioxidant, anti-
inflammatory, and antitumor properties. However, as the effects of C3G on the …

The role of the PI3K pathway in the regeneration of the damaged brain by neural stem cells after cerebral infarction

SH Koh, EH Lo - Journal of Clinical Neurology, 2015 - synapse.koreamed.org
Neurologic deficits resulting from stroke remain largely intractable, which has prompted
thousands of studies aimed at developing methods for treating these neurologic sequelae …

Mitochondrial dysfunction: cause and consequence of Alzheimer's disease

K Friedland-Leuner, C Stockburger, I Denzer… - Progress in molecular …, 2014 - Elsevier
The etiology of common, nonfamiliar late-onset Alzheimer's disease (LOAD) is only partly
understood and seems to be extremely complex including many genetic and environmental …

Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters …

MM Amin, GF Asaad, RM Abdel Salam, HS El-Abhar… - PloS one, 2014 - journals.plos.org
As a nutritional supplement, coenzyme Q10 (CoQ10) was tested previously in several
models of diabetes and/or insulin resistance (IR); however, its exact mechanisms have not …