The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to
what was generally believed, it is now clear that distinct cell types expressing unique …

The human gustatory system is capable of identifying five major taste qualities: sweet, sour,
bitter, salty and savory (umami), and perhaps several sub-qualities. This is a relatively small …

The ability to sense sour provides an important sensory signal to prevent the ingestion of
unripe, spoiled, or fermented foods. Taste and somatosensory receptors in the oral cavity …

The sense of taste provides animals with valuable information about the nature and quality
of food. Mammals can recognize and respond to a diverse repertoire of chemical entities …

The three members of the T1R class of taste-specific G protein-coupled receptors have been
hypothesized to function in combination as heterodimeric sweet taste receptors. Here we …

The tastes of sugars (sweet) and glutamate (umami) are thought to be detected by T1r
receptors expressed in taste cells. Molecular genetics and heterologous expression …

The chemical senses (smell and taste) have evolved complex repertoires of chemosensory
receptors—G-protein coupled receptors with a seven-transmembrane domain structure. In …

In the past several years, tremendous progress has been achieved with the discovery and
characterization of vertebrate taste receptors from the T1R and T2R families, which are …

We used differential screening of cDNAs from individual taste receptor cells to identify
candidate taste transduction elements in mice. Among the differentially expressed clones …

The T1R receptors, a family of taste-specific class CG proteincoupled receptors, mediate
mammalian sweet and umami tastes. The structure–function relationships of T1R receptors …