Human Ageing Genomic Resources: updates on key databases in ageing research

JP de Magalhães, Z Abidi, GA Dos Santos… - Nucleic acids …, 2024 - academic.oup.com
Ageing is a complex and multifactorial process. For two decades, the Human Ageing
Genomic Resources (HAGR) have aided researchers in the study of various aspects of …

Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity

BA Reinke, H Cayuela, FJ Janzen, JF Lemaître… - Science, 2022 - science.org
Comparative studies of mortality in the wild are necessary to understand the evolution of
aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape …

A collective analysis of lifespan-extending compounds in diverse model organisms, and of species whose lifespan can be extended the most by the application of …

C Berkel, E Cacan - Biogerontology, 2021 - Springer
Research on aging and lifespan-extending compounds has been carried out using diverse
model organisms, including yeast, worms, flies and mice. Many studies reported the …

The expression of O-linked glycosyltransferase GALNT7 in breast cancer is dependent on estrogen-, progesterone-, and HER2-receptor status, with prognostic …

C Berkel, E Cacan - Glycoconjugate journal, 2023 - Springer
GALNT7 is a glycosyltransferase enzyme transferring N-acetylgalactosamine to initiate O-
linked glycosylation in the Golgi apparatus. Breast cancer is the most common cancer in …

Comparative analysis of mammal genomes unveils key genomic variability for human life span

X Farré, R Molina, F Barteri… - Molecular Biology …, 2021 - academic.oup.com
The enormous mammal's lifespan variation is the result of each species' adaptations to their
own biological trade-offs and ecological conditions. Comparative genomics have …

Volcanic event management in the Galápagos Islands, Ecuador

B Bernard, P Ramón, L García, S Hernandez… - Volcanica, 2022 - jvolcanica.org
The volcanoes of Galápagos, Ecuador, are among the most active in the world, with an
average of five eruptions per decade. Monitoring and communication of their activity are …

Fish species lifespan prediction from promoter cytosine‐phosphate‐guanine density

AM Budd, B Mayne, O Berry… - Molecular Ecology …, 2023 - Wiley Online Library
Lifespan is a key attribute of a species' life cycle and varies extensively among major
lineages of animals. In fish, lifespan varies by several orders of magnitude, with reported …

Sex-specific innate immunity and ageing in long-lived fresh water turtles (Kinosternon flavescens: Kinosternidae)

AM Bronikowski, AR Hedrick, GA Kutz, KG Holden… - Immunity & …, 2023 - Springer
Background The progressive deregulation of the immune system with age, termed
immunosenescence, has been well studied in mammalian systems, but studies of immune …

The changes in the p53 protein across the animal kingdom point to its involvement in longevity

M Bartas, V Brázda, A Volná, J Červeň… - International journal of …, 2021 - mdpi.com
Recently, the quest for the mythical fountain of youth has produced extensive research
programs that aim to extend the healthy lifespan of humans. Despite advances in our …

A risk-based assessment to advise the responsible consumption of invertebrates, elasmobranch, and fishes of commercial interest in Mexico

LE Saldaña-Ruiz, A Flores-Guzmán… - Frontiers in Marine …, 2022 - frontiersin.org
The main key drivers of vulnerability for marine species are anthropogenic stressors,
ranging from pollution and fishing to climate change. The widely documented impacts of …