Continuous advances in prehabilitation research over the past several decades have
clarified its role in improving preoperative risk factors, yet the evidence demonstrating …

The approval process for pharmaceuticals has always included a consideration of the trade-
offs between benefits and risks. Until recently, these trade-offs have been made in panel …

Benefit-risk assessment is commonly conducted by drug and medical device developers
and regulators, to evaluate and communicate issues around benefit-risk balance of medical …

Background Benefit–risk assessment (BRA) is used in multiple phases along the health
technology's life-cycle to evaluate the balance between the benefits and risks, as it is …

Robust and transparent formal benefit-risk (BR) analyses for medicinal products represent a
means to better understand the appropriate use of medicinal products, and to maximize their …

Objectives This study aimed to understand the importance of criteria describing methods
(eg, duration, costs, validity, and outcomes) according to decision makers for each decision …

Objectives Quantitative benefit-risk assessment (qBRA) is a structured process to evaluate
the benefit-risk balance of treatment options to support decision making. The ISPOR qBRA …

ABSTRACT Introduction Artificial Intelligence (AI) is becoming increasingly utilized in the
medical device industry as it can address unmet demands in clinical sites and provide more …

A crucial step in the design of a diagnostic test is determining the cutoff point, the threshold
which separates a negative measurement from a positive one. The results of a diagnostic …

Abstract Background and Aims Medical treatment for inflammatory bowel disease has
advanced significantly over the two past decades. The advent of biologics and small …