Conjugates of porphyrinoid-based photosensitizers with cytotoxic drugs: current progress and future directions toward selective photodynamic therapy

VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

[HTML][HTML] Main Strategies for the Synthesis of meso-Arylporphyrins

OI Koifman, TA Ageeva - Russian Journal of Organic Chemistry, 2022 - Springer
Abstract meso-Arylporphyrins as most accessible tetrapyrrole macroheterocycles have
always been the focus of attention from researchers concerned with practically useful …

[HTML][HTML] Macroheterocyclic compounds a key building block in new functional materials and molecular devices

OI Koifman, TA Ageeva, IP Beletskaya… - …, 2020 - cyberleninka.ru
The review discusses the latest advances in the directed synthesis and application of
macroheterocyclic compounds in science, engineering and technology, viz. as catalysts for …

Water-soluble chlorin/arylaminoquinazoline conjugate for photodynamic and targeted therapy

VF Otvagin, NS Kuzmina, LV Krylova… - Journal of Medicinal …, 2019 - ACS Publications
A new water-soluble conjugate, consisting of a chlorin-e 6 photosensitizer part, a 4-
arylaminoquinazoline moiety with affinity to epidermal growth factor receptors, and a …

Synthesis and biological evaluation of new water-soluble photoactive chlorin conjugate for targeted delivery

VF Otvagin, AV Nyuchev, NS Kuzmina… - European Journal of …, 2018 - Elsevier
A new water-soluble conjugate, consisting of a chlorin-based photosensitizing part, and a 4-
arylaminoquinazoline moiety with high potential affinity to an epidermal growth factor …

Organic chemistry. History and mutual relations of universities of Russia

IS Antipin, MA Kazymova, MA Kuznetsov… - Russian Journal of …, 2017 - Springer
The review describes the history of development of organic chemistry in higher schools of
Russia over a period of 170 years, since the emergence of organic chemistry in our country …

Development of novel porphyrin/combretastatin A-4 conjugates for bimodal chemo and photodynamic therapy: Synthesis, photophysical and TDDFT computational …

NS Kuzmina, VF Otvagin, AA Maleev… - … of Photochemistry and …, 2022 - Elsevier
Anticancer photodynamic therapy (PDT) in recent years has gained attention among
therapists due to its low systemic toxicity and non-invasive nature. Today, one of the big …

A first-in-class β-glucuronidase responsive conjugate for selective dual targeted and photodynamic therapy of bladder cancer

VF Otvagin, LV Krylova, NN Peskova… - European Journal of …, 2024 - Elsevier
In this report, we present a novel prodrug strategy that can significantly improve the
efficiency and selectivity of combined therapy for bladder cancer. Our approach involved the …

[PDF][PDF] Органическая химия. История и взаимная связь университетов России

ИС Антипин, МА Казымова, МА Кузнецов… - Журнал органической …, 2017 - isuct.ru
4.4. История и научные достижения кафедры органической химии РХТУ им. ДИ
Менделеева. 4.5. История кафедры органической химии Российского университета …

[HTML][HTML] Synthesis, antibacterial screening and computational studies of quinazoline-4 (3H)-one-triazole conjugates

N Manhas, P Singh, A Singh-Pillay… - Journal of Molecular …, 2023 - Elsevier
A novel series of quinazoline-4 (3H)-one-tagged triazole conjugates were synthesised using
the copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) methodology. All synthesized …