Short-term safety and tolerability profile of 5-methoxy-N, N-dimethyltryptamine in human subjects: a systematic review of clinical trials

A Kwaśny, A Wilkowska, WJ Cubała - Frontiers in Psychiatry, 2024 - frontiersin.org
Introduction Psychedelic agents have regained the attention of pharmaceutical companies
as promising treatments for depressive episodes. 5-Methoxy-N, N-dimethyltryptamine (5 …

5-MeO-DMT in the complete resolution of the consequences of chronic, severe sexual abuse in early childhood—a retrospective case study

M Turkia - 2024 - philpapers.org
MeO-DMT is a psychedelic substance with a short duration of action and intensive effects. Its
therapeutic efficacy and practicality may significantly surpass those of classical psychedelics …

A lasting impact of serotonergic psychedelics on visual processing and behavior

CL West, G Bastos, A Duran, S Nadeem, DA Ricci… - bioRxiv, 2024 - biorxiv.org
Serotonergic psychedelics (eg, psilocybin) have shown potential for treating psychiatric
disorders, with therapeutic effects lasting weeks after a single dose. Predictive processing …

A dual-receptor model of serotonergic psychedelics: therapeutic insights from simulated cortical dynamics

A Juliani, V Chelu, L Graesser, A Safron - bioRxiv, 2024 - biorxiv.org
Serotonergic psychedelics have been identified as promising next-generation therapeutic
agents in the treatment of mood and anxiety disorders. While their efficacy has been …

Ketamine in severe, highly treatment-resistant depression—a retrospective case study and a perspective

M Turkia - 2024 - philpapers.org
Ketamine is a well-known and widely available general anesthetic from the 1960s that, in
sub-anesthetic doses, has been adopted in a limited manner for the treatment of acute …

On serotonin, psychedelics, entactogens and psychoplastogens in depression, anxiety, post-traumatic stress, and related disorders.

D Hoyer - Authorea Preprints, 2024 - advance.sagepub.com
There is controversy about a causal role of serotonin (5-HT) in depression, some arguing
that there is no proof for impaired brain 5-HT function in depressed patients. Major …

Relaxed Beliefs After Psychedelics: From Sensory Processing to Mystical States

CLW Jacobs - 2024 - scholarworks.gsu.edu
This dissertation explores the lasting impact of psychedelic use on brain networks, ranging
from basic sensory processing to abstract mystical experiences. Recent research has …