The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

The progress of gut microbiome research related to brain disorders

S Zhu, Y Jiang, K Xu, M Cui, W Ye, G Zhao… - Journal of …, 2020 - Springer
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …

[HTML][HTML] The brain-gut-microbiome axis

CR Martin, V Osadchiy, A Kalani, EA Mayer - Cellular and molecular …, 2018 - Elsevier
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-
microbiome axis. Gut microbes communicate to the central nervous system through at least …

[HTML][HTML] The central nervous system and the gut microbiome

G Sharon, TR Sampson, DH Geschwind… - Cell, 2016 - cell.com
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

GB Rogers, DJ Keating, RL Young, ML Wong… - Molecular …, 2016 - nature.com
The human body hosts an enormous abundance and diversity of microbes, which perform a
range of essential and beneficial functions. Our appreciation of the importance of these …

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

G De Palma, MDJ Lynch, J Lu, VT Dang… - Science translational …, 2017 - science.org
Irritable bowel syndrome (IBS) is a common disorder characterized by altered gut function
and often is accompanied by comorbid anxiety. Although changes in the gut microbiota have …

Gut/brain axis and the microbiota

EA Mayer, K Tillisch, A Gupta - The Journal of clinical …, 2015 - Am Soc Clin Investig
Tremendous progress has been made in characterizing the bidirectional interactions
between the central nervous system, the enteric nervous system, and the gastrointestinal …

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

SM O'Mahony, G Clarke, YE Borre, TG Dinan… - Behavioural brain …, 2015 - Elsevier
The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

The microbiome and host behavior

HE Vuong, JM Yano, TC Fung… - Annual review of …, 2017 - annualreviews.org
The microbiota is increasingly recognized for its ability to influence the development and
function of the nervous system and several complex host behaviors. In this review, we …

[HTML][HTML] Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential

R Guo, LH Chen, C Xing, T Liu - British journal of anaesthesia, 2019 - Elsevier
The relationship between gut microbiota and neurological diseases, including chronic pain,
has received increasing attention. The gut microbiome is a crucial modulator of visceral …