Recent advances in traumatic brain injury

A Khellaf, DZ Khan, A Helmy - Journal of neurology, 2019 - Springer
Traumatic brain injury (TBI) is the most common cause of death and disability in those aged
under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income …

Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Mitochondria in traumatic brain injury and mitochondrial‐targeted multipotential therapeutic strategies

G Cheng, R Kong, L Zhang… - British journal of …, 2012 - Wiley Online Library
Traumatic brain injury (TBI) is a major health and socioeconomic problem throughout the
world. It is a complicated pathological process that consists of primary insults and a …

Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold

X Zhu, C Bührer, S Wellmann - Cellular and molecular life sciences, 2016 - Springer
Cold-inducible RNA-binding protein (CIRP) and RNA-binding motif protein 3 (RBM3) are
two evolutionarily conserved RNA-binding proteins that are transcriptionally upregulated in …

[HTML][HTML] The cellular mechanisms of neuronal swelling underlying cytotoxic edema

RL Rungta, HB Choi, JR Tyson, A Malik… - Cell, 2015 - cell.com
Cytotoxic brain edema triggered by neuronal swelling is the chief cause of mortality
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …

The emerging roles of microRNAs in CNS injuries

OG Bhalala, M Srikanth, JA Kessler - Nature Reviews Neurology, 2013 - nature.com
The consequences of injuries to the CNS are profound and persistent, resulting in
substantial burden to both the individual patient and society. Existing treatments for CNS …

Glial fibrillary acidic protein as a biomarker in severe traumatic brain injury patients: a prospective cohort study

J Lei, G Gao, J Feng, Y Jin, C Wang, Q Mao, J Jiang - Critical care, 2015 - Springer
Introduction Glial fibrillary acidic protein (GFAP) may serve as a serum marker of traumatic
brain injury (TBI) that can be used to monitor biochemical changes in patients and gauge the …

Neuroprotection in stroke: past, present, and future

A Majid - International Scholarly Research Notices, 2014 - Wiley Online Library
Stroke is a devastating medical condition, killing millions of people each year and causing
serious injury to many more. Despite advances in treatment, there is still little that can be …

Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities

B Hakiminia, B Alikiaii, F Khorvash… - Fundamental & …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is one of the most prevalent causes of permanent physical and
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …

What's new in traumatic brain injury: update on tracking, monitoring and treatment

C Reis, Y Wang, O Akyol, WM Ho… - International journal of …, 2015 - mdpi.com
Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …