Transforming growth factor-beta (TGF-β) signaling is one of the important cellular pathways
that play key roles for tissue maintenance. In particular, it is important in the context of …

Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …

Complexity in mechanisms that drive cancer development and progression is exemplified by
the transforming growth factor β (TGF-β) signaling pathway, which suppresses early-stage …

Transforming growth factor-β (TGF-β) has attracted attention as a tumor suppressor because
of its potent growth-suppressive effect on epithelial cells. Dysregulation of the TGF-β …

Background/Aims: Extracellular vesicles (EVs), including microvesicles and exosomes,
deliver bioactive cargo mediating intercellular communication in physiological and …

According to data from 2020, Slovakia has long been among the top five countries with the
highest incidence rate of colorectal cancer (CRC) worldwide, and the rate is continuing to …

The heterogeneous nature of extracellular vesicles (EVs) creates the need for single EV
characterization techniques. However, many common biochemical and functional EV …

Background Multiple molecular expression alterations, particularly in non‐coding RNAs,
play fundamental roles in the regulations of cellular processes and may relate to the …

Extracellular vesicles have emerged as important mediators of cell-to-cell communication in
the pathophysiology of fibrotic diseases. One such disease is Peyronie's disease (PD), a …

Colorectal cancer (CRC) is one of the most common types of cancer and one of the leading
causes of mortality worldwide. MicroRNAs (miRNAs) play central roles in normal cell …