[HTML][HTML] A review on the role of pilocarpine on the management of xerostomia and the importance of the topical administration systems development

A Kapourani, KN Kontogiannopoulos, P Barmpalexis - Pharmaceuticals, 2022 - mdpi.com
Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and
speaking/swallowing difficulties, factors that may significantly degrade patients' life, socially …

Non‐pharmacologic interventions for management of radiation‐induced dry mouth: A systematic review

S Khamdi, O Matangkasombut, A Lam‐Ubol - Oral diseases, 2023 - Wiley Online Library
Objectives Radiation‐induced dry mouth negatively impacts patients' oral health and quality
of life. Currently, evidence‐based recommendation for non‐pharmacologic interventions is …

[HTML][HTML] Xerostomia and its cellular targets

YJ Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Xerostomia, the subjective feeling of a dry mouth associated with dysfunction of the salivary
glands, is mainly caused by radiation and chemotherapy, various systemic and autoimmune …

[HTML][HTML] Prediction of xerostomia in elderly based on clinical characteristics and salivary flow rate with machine learning

YH Lee, JH Won, QS Auh, YK Noh, SW Lee - Scientific Reports, 2024 - nature.com
Xerostomia may be accompanied by changes in salivary flow rate and the incidence
increases in elderly. We aimed to use machine learning algorithms, to identify significant …

[HTML][HTML] A review of the role of natural products as treatment approaches for xerostomia

KN Kontogiannopoulos, A Kapourani, I Gkougkourelas… - Pharmaceuticals, 2023 - mdpi.com
Xerostomia, commonly known as dry mouth, is a widespread oral health malfunction
characterized by decreased salivary flow. This condition results in discomfort, impaired …

[HTML][HTML] Remineralization of teeth with casein phosphopeptide-amorphous calcium phosphate: analysis of salivary pH and the rate of salivary flow

L Alkarad, M Alkhouli, M Dashash - BDJ open, 2023 - nature.com
Aim To investigate the changes of salivary flow rate and salivary pH of Syrian children with
mixed dentition following application of Casein Phosphopeptide-Amorphous Calcium …

Oxidative stress–mediated proapoptosis signaling: A novel theory on the mechanism underlying the pathogenesis of burning mouth syndrome

S Heiliczer, R Yanko, Y Sharav, DJ Aframian… - The Journal of the …, 2024 - Elsevier
Background Burning mouth syndrome (BMS) is a chronic oral pain disorder characterized by
a generalized burning sensation in the oral mucosa without apparent medical or dental …

Quality by design approach for fabrication of extended-release buccal films for xerostomia employing hot-melt extrusion technology

RM Elkanayati, AY Darwesh, I Taha, H Wang… - European Journal of …, 2024 - Elsevier
The study endeavors the fabrication of extended-release adipic acid (APA) buccal films
employing a quality by design (QbD) approach. The films intended for the treatment of …

[HTML][HTML] Common precipitating factors of xerostomia in elderly

FNA Sutarjo, MF Rinthani… - Journal of Health …, 2024 - thieme-connect.com
Xerostomia is a subjective sign of dry mouth t may or may not be accompanied by objective
signs of hyposalivation. The condition of xerostomia has been associated with increasing …

[HTML][HTML] Comparison of the 1 and 2% pilocarpine mouthwash in a xerostomic population: a randomized clinical trial

B Motamed, A Alaee, A Azizi, H Jahandar, MJK Fard… - BMC Oral Health, 2022 - Springer
Aims & background Pilocarpine is an accepted treatment for xerostomia, but limited research
has been conducted on the oral, topical form. The present study aimed to compare the …