Melatonin as a multifunctional modulator: emerging insights into its role in health, reproductive efficiency, and productive performance in livestock

A Afzal - Frontiers in Physiology, 2024 - frontiersin.org
Melatonin, a pleiotropic hormone plays a vital role in enhancing livestock performance not
only by regulating circadian rhythms but also by exhibiting antioxidant, immunomodulatory …

Differential expression of inflammatory cytokines, prostaglandin synthases and secretory leukocyte protease inhibitor in the endometrium and circulation in different …

JK Sasidharan, MK Patra, JA Khan, AK Singh… - Theriogenology, 2023 - Elsevier
Cystic endometrial hyperplasia (CEH)-pyometra (CEH-P) is one of the most common
reproductive disorders in bitches, posing a risk to both future fertility and life. The aims of the …

Kisspeptin-10 promotes progesterone synthesis in bovine ovarian granulosa cells via downregulation of microRNA-1246

L Guo, H Xu, Y Li, H Liu, J Zhao, W Lu, J Wang - Genes, 2022 - mdpi.com
The objective of this study was to clarify the effect of kisspeptin-10 (kp-10) on the synthesis of
progesterone (P4) in bovine granulosa cells (BGCs) and its mechanisms via microRNA …

Impact of Perinatal Coexposure to Chlorpyrifos and a High-Fat Diet on Kisspeptin and GnRHR Presence and Reproductive Organs

M Lahimer, N Djekkoun, S Tricotteaux-Zarqaoui… - Toxics, 2023 - mdpi.com
Emerging evidence has indicated the involvement of extrahypothalamic Kisspeptin and
GnRHR in reproductive function. In this study, we evaluate if maternal exposure to the …

Kisspeptin promotes follicular development through its effects on modulation of P450 aromatase expression and steroidogenesis in sheep ovarian follicles

S Venkata Ratna, T Prasada Rao… - … in Domestic Animals, 2023 - Wiley Online Library
The present study was conducted to ascertain whether the role of kisspeptin in promoting in
vitro development of preantral follicles was through the regulation of P450 aromatase gene …

Effect of disulfiram on the reproductive capacity of female mice

M Teng, Y Luo, C Wang, A Lei - International Journal of Molecular …, 2023 - mdpi.com
In the process of assisted reproduction, the high-oxygen in vitro environment can easily
cause oxidative damage to oocytes. Disulfiram (DSF) can play an anti-oxidant or pro-oxidant …

Enhancement of progesterone biosynthesis via kisspeptin stimulation: Upregulation of steroidogenic transcripts and phosphorylated extracellular signal-regulated …

MP Thejaswini, MK Patra, R Sharma, MRA Raza… - Theriogenology, 2024 - Elsevier
Abstract The presence of Kisspeptin (Kp) and its receptors in the corpus luteum (CL) of
buffalo has recently been demonstrated. In this study, we investigated the role of Kp in the …

Kisspeptin stimulates oestradiol biosynthesis by upregulating steroidogenic transcripts and proliferation markers in the bubaline granulosa cells in vitro

R Sharma, MK Patra, TM Puttanarsappa… - … in Domestic Animals, 2024 - Wiley Online Library
Kisspeptin (Kp), an upstream regulator of GnRH release, is essential for the development
and function of reproductive axis. Previously, we demonstrated the localization of Kp and its …

[PDF][PDF] Kisspeptin-10 promotes progesterone synthesis in bovine ovarian granulosa cells via downregulation of microRNA-1246. Genes (Basel). 2022; 13 (2): 298 …

L Guo, H Xu, Y Li, H Liu, J Zhao, W Lu, J Wang - 2022 - academia.edu
The objective of this study was to clarify the effect of kisspeptin-10 (kp-10) on the synthesis of
progesterone (P4) in bovine granulosa cells (BGCs) and its mechanisms via microRNA …

[PDF][PDF] Exploring the impact of exogenous Kisspeptin-10 on ovarian follicular development and estrus behaviour in Lakhimi cows of Assam

A DATTA, A BARUAH, A BORA, D DUTTA… - The Indian Journal of …, 2024 - epubs.icar.org.in
The present study was carried out to assess the influence of exogenous intravenous
kisspeptin-10 on the follicular dynamics, hormonal profile, and expression pattern of KiSS1 …