Rfam 14: expanded coverage of metagenomic, viral and microRNA families

I Kalvari, EP Nawrocki… - Nucleic Acids …, 2021 - academic.oup.com
Rfam is a database of RNA families where each of the 3444 families is represented by a
multiple sequence alignment of known RNA sequences and a covariance model that can be …

FOXO family isoforms

BF Santos, I Grenho, PJ Martel, BI Ferreira… - Cell Death & …, 2023 - nature.com
FOXO family of proteins are transcription factors involved in many physiological and
pathological processes including cellular homeostasis, stem cell maintenance, cancer …

Potential second-hits in hereditary hemorrhagic telangiectasia

C Bernabeu, P Bayrak-Toydemir, J McDonald… - Journal of Clinical …, 2020 - mdpi.com
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder
that presents with telangiectases in skin and mucosae, and arteriovenous malformations …

Functional implications and clinical potential of MicroRNAs in irritable bowel syndrome: a concise review

LA Bravo-Vázquez, I Medina-Ríos… - Digestive diseases and …, 2023 - Springer
Abstract MicroRNAs (miRNAs) are tiny (20–24 nucleotides long), non-coding, highly
conserved RNA molecules that play a crucial role within the post-transcriptional regulation of …

The mechanistic roles of sirtuins in breast and prostate cancer

CI Onyiba, CJ Scarlett, J Weidenhofer - Cancers, 2022 - mdpi.com
Simple Summary There are diverse reports of the dual role of sirtuin genes and proteins in
breast and prostate cancers. This review discusses the current information on the tumor …

Ultrasensitive detection of MicroRNA in human saliva via rolling circle amplification using a DNA-decorated graphene oxide sensor

P Pitikultham, T Putnin, D Pimalai… - ACS …, 2023 - ACS Publications
MicroRNAs (miRNAs) are a family of conserved small noncoding RNAs whose expression is
associated with many diseases, including cancer. Salivary miRNAs are gaining popularity …

Investigating the role of the microRNA-34/449 family in male infertility: a critical analysis and review of the literature

K Pantos, S Grigoriadis, P Tomara, I Louka… - Frontiers in …, 2021 - frontiersin.org
There is a great body of evidence suggesting that in both humans and animal models the
microRNA-34/449 (miR-34/449) family plays a crucial role for normal testicular functionality …

MicroRNA-mediated epigenetic regulation of inflammasomes in inflammatory responses and immunopathologies

YS Yi - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Inflammation represents the first-line defense mechanism of the host against pathogens and
cellular stress. One of the most critical inflammatory responses is characterized by the …

Circulating miRNAs as a predictive biomarker of the progression from prediabetes to diabetes: outcomes of a 5-year prospective observational study

I Sidorkiewicz, M Niemira, K Maliszewska… - Journal of Clinical …, 2020 - mdpi.com
Due to a global increase in the prevalence of type 2 diabetes mellitus (T2DM), there is an
urgent need for early identification of prediabetes, as these people have the highest risk of …

MicroRNA-183/96/182 cluster in immunity and autoimmunity

Z Wang, R Dai, SA Ahmed - Frontiers in Immunology, 2023 - frontiersin.org
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression in
ubiquitous biological processes, including immune-related pathways. This review focuses …