D-Amino acid oxidase (DAAO) is an FAD-containing flavoenzyme that catalyzes with
absolute stereoselectivity the oxidative deamination of all natural D-amino acids, the only …

The stereoselective flavoenzyme D-amino acid oxidase (DAAO) catalyzes the oxidative
deamination of neutral and polar D-amino acids producing the corresponding α-keto acids …

Molecular dynamics (MD) is a powerful computational technique that allows us to simulate
the interactions of atoms and molecules of a system over a specific period of time through …

D-amino acid oxidase (DAO) maintains the intracellular d-serine level which modulates the
activity of the N-methyl-d-aspartate receptor and its dysfunction has been linked to several …

We have investigated a pathogenic mutation in D-amino acid oxidase (DAO), DAOR199W,
associated with familial Amyotrophic Lateral Sclerosis (ALS) that impairs D-serine …

Biological Chirality describes this occurrence, its history, and early research around the
topic. The work covers analytical methods for observing the phenomenon, providing current …

Many pathogenetic mechanisms have been proposed for amyotrophic lateral sclerosis
(ALS). Recently, there have been emerging suggestions of a possible role for the gut …

Impaired enzymatic activity in D-amino acid oxidase (DAAO) caused by missense mutations
has been shown to trigger amyotrophic lateral sclerosis (ALS) through an abnormal …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a terminal adult-onset neuromuscular
disorder. Our group has been studying this illness and previously reported novel mutations …

Neurotropic viruses target the central nervous system through various mechanisms: they
have the potential to modulate synaptic plasticity, causing cognitive impairments by blocking …