Potential of natural antioxidant compound in Cymbopogon nardus as anti-cancer drug via HSP-70 inhibitor: A bioinformatics approach

R Solekha, PAI Setiyowati… - Jurnal Teknologi …, 2022 - teknolabjournal.com
Citronella grass (Cymbopogon nardus) is a plant containing many metabolite compounds
which prevent and treat various diseases, one of which is cancer. Antioxidant compounds …

[PDF][PDF] Uji in silico senyawa 2, 6-dihidroksiantraquinon sebagai ligan pada reseptor estrogen alfa

FF Setiawan, EP Istyastono - Jurnal Farmasi Sains dan Komunitas, 2015 - core.ac.uk
Previous studies has shown that estrogen receptor alpha that binds to estrogen may
increase cancer cell proliferation, thus estrogen receptor alpha can be targeted to cure …

[PDF][PDF] Computer-aided design of chalcone derivatives as lead compounds targeting acetylcholinesterase

FDO Riswanto, M Hariono, SH Yuliani… - Indonesian J …, 2017 - academia.edu
One of well-established biological activities for chalcone derivatives is as
acetylcholinesterase inhibitors, which can be developed for the therapy of Alzheimer's …

[PDF][PDF] Binary quantitative structure-activity relationship analysis in retrospective structure based virtual screening campaigns targeting estrogen receptor alpha

EP Istyastono, N Yuniarti, M Hariono… - Asian J. Pharm …, 2017 - repository.usd.ac.id
Objective: The objective of this study is to Construct predictive unbiased structure-based
virtual screening (SBVS) protocols to identify potent ligands for estrogen receptor alpha by …

Ligand based pharmacophore modeling, virtual screening, and molecular docking studies of asymmetrical hexahydro-2H-indazole analogs of curcumin (AIACs) to …

H Hariyanti, K Kurmardi, A Yanuar… - Indonesian Journal of …, 2021 - journal.ugm.ac.id
The estrogen receptor alpha (ERα) plays an important role in breast development and pro-
proliferation signal activation in the normal and cancerous breast. The ERα inhibitors were …

Determination of ligand position in aspartic proteases by correlating tanimoto coefficient and binding affinity with root mean square deviation

S Megantara, MI Iwo, J Levita… - Journal of Applied …, 2016 - japsonline.com
The objective of this study was to develop and validate of Structure-Based Virtual Screening
(SBVS) protocol which was used to select the best pose of inhibitor-aspartic protease …

Introductory chapter: The emerging corner of the omics studies for rational drug design

AA Parikesit - Drug Design-Novel Advances in the Omics Field …, 2021 - books.google.com
The Acceleration of COVID-19 research in Proteomics and Transcriptomics studies occurred
swiftly due to the massive amount of investment and advances in biomanufacturing [1, 2] …

Development of a Graphical User Interface Application to Identify Marginal and Potent Ligands for Estrogen Receptor Alpha

N Yuniarti, S Mungkasi, SH Yuliani… - Indonesian Journal of …, 2019 - journal.ugm.ac.id
Abstract Employing ensemble Protein-Ligand Interaction Fingerprints (ensPLIF) as
descriptors in post retrospective Structure-Based Virtual Screening (SBVS) campaigns …

Binary quantitative structure-activity relationship analysis to increase the predictive ability of structure-based virtual screening campaigns targeting cyclooxygenase-2

EP Istyastono - Indonesian Journal of Chemistry, 2017 - journal.ugm.ac.id
Abstract Structure-Based Virtual Screening (SBVS) campaigns employing Protein-Ligand
Interaction Fingerprints (PLIF) identification have served as a powerful strategy in fragments …

[PDF][PDF] Optimizing Structure-based Virtual Screening protocol to identify phytochemicals as cyclooxygenase-2 inhibitors.

EP Istyastono - Indonesian Journal of Pharmacy/Majalah …, 2016 - pdfs.semanticscholar.org
ABSTRACT By employing Databases of Useful Decoys (DUD) and its enhanced version
(DUD-E), several attempts to construct validated Structure-based Virtual Screening (SBVS) …