Quantifying the benefit of early antibiotic treatment is crucial for decision making and can be
assessed only in observational studies. We performed a systematic review of prospective …

The endothelial integrity, as mechanical barrier against microorganisms and as natural
“anticoagulant”, is crucial for physiologic organ function. Systemic activation of the …

Objective: To gain a better understanding of the epidemiology, microbiology, and outcomes
of early-onset, culture-positive, community-acquired, healthcare-associated, and hospital …

Background Health care–associated pneumonia (HCAP) has been proposed as a new
category of respiratory infection. However, limited data exist to validate this entity. We aimed …

Bloodstream infections (BSI) are a major cause of mortality, morbidity and medical cost, but
few population-based studies have concomitantly evaluated BSI incidence and mortality …

Clin Microbiol Infect 2010; 16: 1408–1413 Abstract Classification of bloodstream infections
(BSIs) as community‐acquired (CA), healthcare‐associated (HCA) and hospital‐acquired …

Background Bloodstream infections (BSI) have been traditionally classified as either
community acquired (CA) or hospital acquired (HA) in origin. However, a third category of …

La bacteriemia conforma un síndrome clínico complejo y en constante transformación que
ocasiona una importante y creciente morbimortalidad. La información sobre la bacteriemia …

OBJECTIVES: Classically, infections have been considered either nosocomial or community-
acquired. Healthcare-associated infection represents a new classification intended to …

Bloodstream infections (BSIs) are among the leading infections in critically ill patients. The
case-fatality rate associated with BSIs in patients admitted to intensive care units (ICUs) …