[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy

Y Wang, H Qi, Y Liu, C Duan, X Liu, T Xia, D Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

The concept of intrinsic versus extrinsic apoptosis

L Lossi - Biochemical Journal, 2022 - portlandpress.com
Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

β‐Sitosterol‐assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line

K Raj R - Journal of biomedical materials research Part A, 2020 - Wiley Online Library
Cancer nanomedicine is an emerging field of cancer therapeutics. Incidence of
hepatocellular carcinoma (HCC) is increasing worldwide, and currently, it is the second …

Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

D Kashyap, VK Garg, N Goel - Advances in protein chemistry and structural …, 2021 - Elsevier
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

Apoptosis in Alzheimer's disease: insight into the signaling pathways and therapeutic avenues

S Kumari, R Dhapola, DHK Reddy - Apoptosis, 2023 - Springer
Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …

Effects and mechanisms of phthalates' action on reproductive processes and reproductive health: a literature review

H Hlisníková, I Petrovičová, B Kolena… - International journal of …, 2020 - mdpi.com
The production of plastic products, which requires phthalate plasticizers, has resulted in the
problems for human health, especially that of reproductive health. Phthalate exposure can …

Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted …

M Liao, R Qin, W Huang, HP Zhu, F Peng… - Journal of Hematology & …, 2022 - Springer
Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Advances in mechanism and regulation of PANoptosis: Prospects in disease treatment

P Zhu, ZR Ke, JX Chen, SJ Li, TL Ma… - Frontiers in …, 2023 - frontiersin.org
PANoptosis, a new research hotspot at the moment, is a cell death pattern in which
pyroptosis, apoptosis, and necroptosis all occur in the same cell population. In essence …

[HTML][HTML] Advances in dietary polysaccharides as anticancer agents: Structure-activity relationship

N Li, C Wang, MI Georgiev, VK Bajpai, R Tundis… - Trends in Food Science …, 2021 - Elsevier
Background The discovery of nutritious dietary supplements and side effect-free
therapeutics are a priority in the current scenario of increasing cancer cases. Natural …

Apoptosis and its therapeutic implications in neurodegenerative diseases

NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …