Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …

MicroRNAs (miRNAs) are found in the circulatory biofluids considering the important
molecules for biomarker study in aging and age-related diseases. Blood or blood …

Bone is a mineralized and elastic connective tissue that provides fundamental functions in
the human body, including mechanical support to the muscles and joints, protection of vital …

Bone microenvironment provides growth and survival signals essential for osteosarcoma
(OS) initiation and progression. OS cells regulate communications inside tumor …

Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass
and microarchitecture, which compromises bone strength. It is a complex multifactorial …

Osteoporosis and other manifestations of bone disease are frequent in patients with
systemic mastocytosis (SM) in association with the presence of mast cell infiltrates in bone …

Senile osteoporosis is one of the major health problems in an aging society. Decreased
bone formation due to osteoblast dysfunction may be one of the causes of aging-related …

MicroRNAs are small, noncoding single-stranded RNAs that have emerged as important
posttranscriptional regulators of gene expression, with an essential role in vertebrate …

Osteoporosis is the most prevailing primary bone disease and a growing health care
burden. The aim of this study was to clarify the functional roles and mechanisms of the circ …

Osteoporosis is a common age-related disorder characterized by low bone mass and
deterioration in bone microarchitecture, leading to increased skeletal fragility and fracture …