Leishmaniasis in humans: drug or vaccine therapy?
M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …
[HTML][HTML] Nanosystems for the encapsulation of natural products: The case of chitosan biopolymer as a matrix
A Detsi, E Kavetsou, I Kostopoulou, I Pitterou… - Pharmaceutics, 2020 - mdpi.com
Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly
interesting biomaterialover the past few years. It constitutes a novel perspective in drug …
interesting biomaterialover the past few years. It constitutes a novel perspective in drug …
[HTML][HTML] Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral …
The development of an effective oral therapeutics is an immediate need for the control and
elimination of visceral leishmaniasis (VL). We exemplify the preparation and optimization of …
elimination of visceral leishmaniasis (VL). We exemplify the preparation and optimization of …
Exploring the current landscape of chitosan-based hybrid nanoplatforms as cancer theragnostic
In the last decade, investigators have put significant efforts to develop several diagnostic
and therapeutic strategies against cancer. Many novel nanoplatforms, including lipidic …
and therapeutic strategies against cancer. Many novel nanoplatforms, including lipidic …
Nanostructured delivery systems with improved leishmanicidal activity: a critical review
N Bruni, B Stella, L Giraudo, C Della Pepa… - International journal …, 2017 - Taylor & Francis
Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …
genus Leishmania, which are responsible for numerous clinical manifestations, such as …
Sirolimus loaded chitosan functionalized poly (lactic-co-glycolic acid)(PLGA) nanoparticles for potential treatment of age-related macular degeneration
The usefulness of sirolimus (SIR) in the treatment of diseases that involve retinal
degeneration like age-related macular degeneration (AMD) has been well documented …
degeneration like age-related macular degeneration (AMD) has been well documented …
Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis
The goal of study was to develop micellar formulation of Amphotericin B (AmB) to improve its
antileishmanial efficacy. AmB loaded pluronic F127 (PF 127) micelles were developed and …
antileishmanial efficacy. AmB loaded pluronic F127 (PF 127) micelles were developed and …
Fucoidan-mediated targeted delivery of dasatinib-loaded nanoparticles amplifies apoptosis and endows cytotoxic potential in triple-negative breast cancer
Dasatinib (DST) is a tyrosine kinase inhibitor with established antiproliferative activity in
Triple-negative breast cancer. Conventional treatment strategies with DST have several …
Triple-negative breast cancer. Conventional treatment strategies with DST have several …
[HTML][HTML] Micromolding of amphotericin-B-loaded methoxyethylene–maleic anhydride copolymer microneedles
S Azizi Machekposhti, AK Nguyen, L Vanderwal… - Pharmaceutics, 2022 - mdpi.com
Biocompatible and biodegradable materials have been used for fabricating polymeric
microneedles to deliver therapeutic drug molecules through the skin. Microneedles have …
microneedles to deliver therapeutic drug molecules through the skin. Microneedles have …
[HTML][HTML] Recuperating biopharmaceutical aspects of amphotericin B and paromomycin using a chitosan functionalized nanocarrier via oral route for enhanced anti …
S Parvez, G Yadagiri, A Karole, OP Singh… - Frontiers in cellular …, 2020 - frontiersin.org
The design and development of new pharmaceutical formulations for the existing anti-
leishmanial is a new strategic alternate to improve efficacy and safety rather than new drug …
leishmanial is a new strategic alternate to improve efficacy and safety rather than new drug …