Endogenous opiates and behavior: 2022
RJ Bodnar - Peptides, 2023 - Elsevier
This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …
research concerning the endogenous opioid system, summarizing articles published during …
Long-access heroin self-administration induces region specific reduction of grey matter volume and microglia reactivity in the rat
N Cannella, S Tambalo, V Lunerti, G Scuppa… - Brain, Behavior, and …, 2024 - Elsevier
In opioid use disorder (OUD) patients, a decrease in brain grey matter volume (GMV) has
been reported. It is unclear whether this is the consequence of prolonged exposure to …
been reported. It is unclear whether this is the consequence of prolonged exposure to …
Active vs passive novelty-related strategies: Sex differences in exploratory behaviour and monoaminergic systems
K Liiver, S Imbeault, M Školnaja, T Kaart… - Behavioural Brain …, 2023 - Elsevier
Sex differences are apparent in numerous behavioural characteristics. In order to compare
and characterise male and female variability of exploratory behaviour, 365 male and 401 …
and characterise male and female variability of exploratory behaviour, 365 male and 401 …
A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency
BN Kuhn, N Cannella, AD Crow, V Lunerti, A Gupta… - bioRxiv, 2024 - biorxiv.org
Objective The behavioral and diagnostic heterogeneity within human opioid use disorder
(OUD) diagnosis is not readily captured in current animal models, limiting translational …
(OUD) diagnosis is not readily captured in current animal models, limiting translational …
The effects of sleep restriction during abstinence on oxycodone seeking: Sex-dependent moderating effects of behavioral and hypothalamic-pituitary-adrenal axis …
During opioid use and abstinence, sleep disturbances are common and are thought to
exacerbate drug craving. In this study, we tested the hypothesis that sleep restriction during …
exacerbate drug craving. In this study, we tested the hypothesis that sleep restriction during …
Generalization of a positive-feature interoceptive morphine occasion setter across the rat estrous cycle
Introduction Interoceptive stimuli elicited by drug administration acquire conditioned
modulatory properties of the induction of conditioned appetitive behaviours by exteroceptive …
modulatory properties of the induction of conditioned appetitive behaviours by exteroceptive …
Differences in drug intake levels (high versus low takers) do not necessarily imply distinct drug user types: insights from a new cluster-based model
DM Castaneda, M Job - bioRxiv, 2024 - biorxiv.org
Background: Classifying psychostimulant users as high and low responders based on
median split of drug intake levels has face-validity: these appear to be different types of drug …
median split of drug intake levels has face-validity: these appear to be different types of drug …
Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats
The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle
the biological mechanisms contributing to individual differences in OUD vulnerability. OUD …
the biological mechanisms contributing to individual differences in OUD vulnerability. OUD …
Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats
The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle
the biological mechanisms contributing to individual differences in OUD vulnerability. OUD …
the biological mechanisms contributing to individual differences in OUD vulnerability. OUD …
The effects of cocaine and heroin polydrug use on drug-related motivation and affective state in Lister-Hooded rats
K Adamatzky - 2023 - sussex.figshare.com
Cocaine and heroin are commonly abused drugs and are often used together. Such
polydrug use increases the risk of psychopathology, overdose, and poorer treatment …
polydrug use increases the risk of psychopathology, overdose, and poorer treatment …