Acute limb ischemia is a common medical condition resulting from arterial embolization, in
situ thrombosis, trauma, and other causes. The severity of injury is related to the duration of …

Morbidity and mortality after revascularization of acute ischemic limbs remain high, despite
many surgical improvements during the last decades. To a large extent, this is related to …

BACKGROUND:: Despite advances in revascularization following extremity vascular injury,
the relationship between time to restoration of flow and functional limb salvage is unknown …

Hypoxia and reoxygenation were studied in rat hearts and ischemia and reperfusion in rat
hindlimbs. Free radicals are known to be generated through these events and to propagate …

Background: Extremity ischemia/reperfusion has been studied mostly in small-animal
models with limited characterization of neuromuscular or functional outcome. The objective …

OBJECTIVE: Reperfusion of the limb after acute and persistent ischemia is associated with
high rates of morbidity and mortality despite complete revascularization. Although …

The pathogenesis of the reperfusion syndrome is complex and as yet not fully elucidated. It
is characterized by the development of increased microvascular permeability, oedema and …

Sitosterolemia is an autosomal recessive disorder caused by mutations in the ABCG5 or
ABCG8 half-transporter genes. These mutations disrupt the mechanism that distinguishes …

Apesar dos avanços da medicina, persiste alta a incidência da oclusão arterial aguda dos
membros, decorrente do aumento da longevidade e, conseqüentemente, da aterosclerose …

Background Controlled limb reperfusion has been shown to prevent the deleterious effects
of ischemia–reperfusion (IR) syndrome following revascularization of acute limb ischemia …