The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

Fatty liver disease comprises a spectrum ranging from simple steatosis to steatohepatitis
which can progress to liver cirrhosis and hepatocellular cancer. Hepatic lipotoxicity may …

Objective We evaluated the influence of the renin–angiotensin system (RAS) on intestinal
inflammation and fibrosis. Design Cultured human colonic myofibroblast proliferation and …

Portal hypertension and bleeding from gastroesophageal varices is the major cause of
morbidity and mortality in patients with cirrhosis. Portal hypertension is initiated by increased …

Metabolic syndrome is common among liver transplant recipients before and after
transplantation. The components of metabolic syndrome are often exacerbated in the post …

Background The renin‐angiotensin system (RAS) is a homeostatic pathway widely known to
regulate cardiovascular and renal physiology; however, little is known about its influence in …

Currently, nonalcoholic steatohepatitis (NASH) is the second leading indication for liver
transplantation (LT), behind alcohol‐related liver disease. After transplant, both recurrent …

In the last three decades, the understanding of the renin angiotensin system (RAS) has been
changed by the discoveries of functional local systems, novel biologically active peptides …

The genetic variant A1 of bovine β-casein (β-Cn) presents a His residue at a position 67 of
the mature protein. This feature makes the Ile66-His67 bond more vulnerable to enzymatic …

Nonalcoholic fatty liver disease (NAFLD) is the commonest liver disease in Western
countries. Treatment of NAFLD is currently based on lifestyle measures and no effective …