Analysis methods for large-scale neuronal recordings

C Stringer, M Pachitariu - Science, 2024 - science.org
Simultaneous recordings from hundreds or thousands of neurons are becoming routine
because of innovations in instrumentation, molecular tools, and data processing software …

Interconnected neural circuits mediating social reward

J Isaac, M Murugan - Trends in Neurosciences, 2024 - cell.com
Across species, social behaviors are shaped and maintained through positive reinforcement
of affiliative social interactions. As with nonsocial rewards, the reinforcing properties of social …

Distributed and specific encoding of sensory, motor, and decision information in the mouse neocortex during goal-directed behavior

A Oryshchuk, C Sourmpis, J Weverbergh, R Asri… - Cell Reports, 2024 - cell.com
Goal-directed behaviors involve coordinated activity in many cortical areas, but whether the
encoding of task variables is distributed across areas or is more specifically represented in …

Mating proximity blinds threat perception

L Cazalé-Debat, L Scheunemann, M Day… - Nature, 2024 - nature.com
Romantic engagement can bias sensory perception. This 'love blindness' reflects a common
behavioural principle across organisms: favouring pursuit of a coveted reward over potential …

High-dimensional cortical signals reveal rich bimodal and working memory-like representations among S1 neuron populations

SS Kristensen, K Kesgin, H Jörntell - Communications biology, 2024 - nature.com
Complexity is important for flexibility of natural behavior and for the remarkably efficient
learning of the brain. Here we assessed the signal complexity among neuron populations in …

Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex

J Isaac, SC Karkare, H Balasubramanian… - Nature …, 2024 - nature.com
The reinforcing nature of social interactions is necessary for the maintenance of appropriate
social behavior. However, the neural substrates underlying social reward processing and …

Vagus nerve stimulation during training fails to improve learning in healthy rats

AM Carroll, DT Pruitt, JR Riley, TT Danaphongse… - Scientific Reports, 2024 - nature.com
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory
and motor events can increase neuroplasticity in networks related to these events and might …

Differential representation of sensory information and behavioral choice across layers of the mouse auditory cortex

R Steinfeld, A Tacão-Monteiro, A Renart - Current Biology, 2024 - cell.com
The activity of neurons in sensory areas sometimes covaries with upcoming choices in
decision-making tasks. However, the prevalence, causal origin, and functional role of choice …

Amygdala and cortex relationships during learning of a sensory discrimination task

D Levitan, A Gilad - Journal of Neuroscience, 2024 - jneurosci.org
During learning of a sensory discrimination task, the cortical and subcortical regions display
complex spatiotemporal dynamics. During learning, both the amygdala and cortex link …

Interareal synaptic inputs underlying whisking-related activity in the primary somatosensory barrel cortex

M Kawatani, K Horio, M Ohkuma, WR Li… - Journal of …, 2024 - Soc Neuroscience
Body movements influence brain-wide neuronal activities. In the sensory cortex,
thalamocortical bottom-up inputs and motor-sensory top-down inputs are thought to affect …