The growing number of multi-omics studies demands clear conceptual workflows coupled
with easy-to-use software tools to facilitate data analysis and interpretation. This protocol …

Genomics is advancing towards data-driven science. Through the advent of high-throughput
data generating technologies in human genomics, we are overwhelmed with the heap of …

Genome-wide association studies (GWAS) have revealed thousands of genetic loci that
underpin the complex biology of many human traits. However, the strength of GWAS–the …

Morphological and gene expression profiling can cost-effectively capture thousands of
features in thousands of samples across perturbations by disease, mutation, or drug …

Given the increasing research activity on epigenetics to monitor human diseases and its
connection with lifestyle and environmental expositions, the field of epigenetics has attracted …

Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …

DNA methylation is an epigenetic modification that has consistently been shown to be linked
with a variety of human traits and diseases. Because DNA methylation is dynamic and …

Despite constant research and public policy efforts, the obesity epidemic continues to be a
major public health threat, and new approaches are urgently needed. It has been shown that …

Chile pepper (Capsicum spp.) is a major culinary, medicinal, and economic crop in most
areas of the world. For more than hundreds of years, chile peppers have “defined” the state …

Effective pharmacological management of pain associated with tissue pathology is an unmet
medical need. Transcriptional modifications in nociceptive pathways are pivotal for the …