The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …

Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis

MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

Infection prevention and control guideline for cystic fibrosis: 2013 update

L Saiman, JD Siegel, JJ LiPuma, RF Brown… - Infection Control & …, 2014 - cambridge.org
The 2013 Infection Prevention and Control (IP&C) Guideline for Cystic Fibrosis (CF) was
commissioned by the CF Foundation as an update of the 2003 Infection Control Guideline …

The changing microbial epidemiology in cystic fibrosis

JJ LiPuma - Clinical microbiology reviews, 2010 - Am Soc Microbiol
Infection of the airways remains the primary cause of morbidity and mortality in persons with
cystic fibrosis (CF). This review describes salient features of the epidemiologies of microbial …

Pathophysiology and management of pulmonary infections in cystic fibrosis

RL Gibson, JL Burns, BW Ramsey - American journal of respiratory …, 2003 - atsjournals.org
This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

Clinical significance of microbial infection and adaptation in cystic fibrosis

AR Hauser, M Jain, M Bar-Meir… - Clinical microbiology …, 2011 - Am Soc Microbiol
SUMMARY A select group of microorganisms inhabit the airways of individuals with cystic
fibrosis. Once established within the pulmonary environment in these patients, many of …

Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis

Z Li, MR Kosorok, PM Farrell, A Laxova, SEH West… - Jama, 2005 - jamanetwork.com
ContextAlthough Pseudomonas aeruginosa is the most common virulent respiratory
pathogen in cystic fibrosis (CF), the longitudinal development of P aeruginosa infection and …

Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches

H Lund-Palau, AR Turnbull, A Bush… - Expert review of …, 2016 - Taylor & Francis
Pseudomonas aeruginosa is a remarkably versatile environmental bacterium with an
extraordinary capacity to infect the cystic fibrosis (CF) lung. Infection with P. aeruginosa …

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

AK Miller, MK Brannon, L Stevens… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Pseudomonas aeruginosa can develop resistance to polymyxin and other cationic
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …

Newborn screening for cystic fibrosis: evaluation of benefits and risks and recommendations for state newborn screening programs

SD Grosse, CA Boyle, JR Botkin, AM Comeau… - 2004 - repository.escholarship.umassmed …
In November 2003, CDC and the Cystic Fibrosis Foundation cosponsored a workshop to
review the benefits and risks associated with newborn screening for cystic fibrosis (CF). This …