Future research that will define the endothelial contribution to stiffness-related
cardiovascular disease may provide new targets for intervention to restore endothelial …

Vascular aging, early vascular aging or supernormal vascular aging are concepts used for
estimating the cardiovascular risk at a certain age. From the famous line of Thomas …

Abstract Purpose of Review Cardiovascular diseases are the leading cause of mortality
globally. Identifying patients at risk is important to initiate preventive strategies. Over the last …

Endothelial dysfunction often precedes the development of cardiovascular diseases,
including heart failure. The cardioprotective benefits of sodium-glucose cotransporter 2 …

Nano plastics (NPs) have been a significant threat to human health and are known to cause
premature endothelial senescence. Endothelial senescence is considered one of the …

Aims The beneficial cardiovascular effects of sodium-glucose cotransporter 2 (SGLT2)
inhibitors irrespective of the presence of diabetes mellitus are nowadays well established …

Atherosclerosis (AS) is a chronic inflammatory disease and leading cause of cardiovascular
diseases. The progression of AS is a multi-step process leading to high morbidity and …

Overloaded glucose levels in several metabolic diseases such as type 2 diabetes (T2D) can
lead to mitochondrial dysfunction and enhanced production of reactive oxygen species …

Arterial stiffness is a hallmark of vascular ageing and results in increased blood flow
pulsatility to the periphery, damaging end-organs such as the heart, kidneys and brain …

Vascular calcification (VC) is a major risk factor for cardiovascular events. A mutual interplay
between inflammation, oxidative stress, apoptosis, and autophagy is implicated in its …