The related metabolic diseases and treatments of obesity

M Yang, S Liu, C Zhang - Healthcare, 2022 - mdpi.com
Obesity is a chronic disease characterized by the abnormal or excessive accumulation of
body fat, affecting more than 1 billion people worldwide. Obesity is commonly associated …

Transcriptome-wide association studies: recent advances in methods, applications and available databases

J Mai, M Lu, Q Gao, J Zeng, J Xiao - Communications Biology, 2023 - nature.com
Genome-wide association study has identified fruitful variants impacting heritable traits.
Nevertheless, identifying critical genes underlying those significant variants has been a …

Mechanisms of sex and gender differences in hypertension

JF Reckelhoff - Journal of Human Hypertension, 2023 - nature.com
The mechanisms that control blood pressure are multifaceted including the sympathetic
nervous system and the renin-angiotensin system leading to vasoconstriction and sodium …

Influence of multiple risk factor control level on cardiovascular outcomes in hypertensive patients

X Peng, M Zhuang, Q Song, J Bai… - European Heart Journal …, 2024 - academic.oup.com
Aims The relationship between the level of baseline risk factor control and cardiovascular
outcomes in hypertensive patients with blood pressure interventions is not well understood …

[HTML][HTML] Reduction of NADPH oxidase 4 in adipocytes contributes to the anti-obesity effect of dihydroartemisinin

H Hua, M Wu, T Wu, Y Ji, L Jin, Y Du, Y Zhang… - Heliyon, 2023 - cell.com
Artemisinin derivatives have been found to have anti-obesity effects recently, but the
mechanism is still controversial. Herein, long-term DHA treatment in obese mice significantly …

Self‐reported sleep duration and quality and cardiovascular diseases among middle‐aged and older Chinese: A 7‐year longitudinal cohort study

Z Lv, Y Ji, C Li, Z Zhao, W Jia, J Hou… - The Journal of Clinical …, 2024 - Wiley Online Library
Cardiovascular disease (CVD) is a leading cause of death worldwide, and several studies
have attempted to identify its risk factors. This study aimed to investigate the association …

Lipid-Lowering Therapy in PURE Poland Cohort Study

P Lubieniecki, M Wołyniec, K Połtyn-Zaradna… - Journal of Clinical …, 2023 - mdpi.com
The aim of this study is to present data on the use of lipid-lowering therapy (LLT) in relation
to calculated cardiovascular risk (CVR) and an additionally defined target LDL-C …

[HTML][HTML] Genetic associations of childhood and adult BMI on chronic heart failure and ischemic stroke: A Mendelian randomization

G Li, H Zhang, J Jiang - IJC Heart & Vasculature, 2024 - Elsevier
Background Obesity has been confirmed to be associated with cardiovascular disease, but
previous studies have focused on adults, and whether childhood obesity is associated with …

Age-specific heterogeneity of genetic susceptibility to cardiovascular disease might have opposite outcomes depending on the presence of prediabetes

C Lee - World Journal of Diabetes, 2024 - pmc.ncbi.nlm.nih.gov
Examining age-specific heterogeneity of susceptibility to cardiovascular disease is also
essential in individuals without prediabetes to determine its relative size and direction …

Dynamic continuous blood extraction from rat heart via noninvasive microdialysis technique

Y Hou, J Bai, Y Zhang, X Meng, S Zhang… - JoVE (Journal of …, 2022 - jove.com
Dynamic analysis of blood components is of great importance in understanding
cardiovascular diseases and their related diseases, such as myocardial infarction …