Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
L Koklesova, A Mazurakova, M Samec, K Biringer… - EPMA Journal, 2021 - Springer
Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
Dysfunctional vascular endothelium as a driver of atherosclerosis: emerging insights into pathogenesis and treatment
Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …
associated with a broad spectrum of cardiovascular diseases including myocardial …
Mechanism of homocysteine-mediated endothelial injury and its consequences for atherosclerosis
D Yuan, J Chu, H Lin, G Zhu, J Qian, Y Yu… - Frontiers in …, 2023 - frontiersin.org
Homocysteine (Hcy) is an intermediate amino acid formed during the conversion from
methionine to cysteine. When the fasting plasma Hcy level is higher than 15 μmol/L, it is …
methionine to cysteine. When the fasting plasma Hcy level is higher than 15 μmol/L, it is …
FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE−/− mice atherosclerosis
L Xu, H Zhang, Y Wang, A Yang, X Dong, L Gu… - Laboratory …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease, and inflammation plays a critical
role in its formation and progression. Elevated serum homocysteine (Hcy) is an independent …
role in its formation and progression. Elevated serum homocysteine (Hcy) is an independent …
Potential synergistic supplementation of NAD+ promoting compounds as a strategy for increasing healthspan
A Sharma, S Chabloz, RA Lapides, E Roider… - Nutrients, 2023 - mdpi.com
Disrupted biological function, manifesting through the hallmarks of aging, poses one of the
largest threats to healthspan and risk of disease development, such as metabolic disorders …
largest threats to healthspan and risk of disease development, such as metabolic disorders …
Research Progress of Flavonoids Regulating Endothelial Function
H Li, Q Zhang - Pharmaceuticals, 2023 - mdpi.com
The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …
[HTML][HTML] Dapagliflozin impedes endothelial cell senescence by activating the SIRT1 signaling pathway in type 2 diabetes
S Tai, Y Zhou, L Fu, H Ding, Y Zhou, Z Yin, R Yang… - Heliyon, 2023 - cell.com
Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) clinically reduce
atherosclerosis and lower blood pressure. However, their impact on endothelial dysfunction …
atherosclerosis and lower blood pressure. However, their impact on endothelial dysfunction …
Cordycepin attenuates palmitic acid-induced inflammation and apoptosis of vascular endothelial cells through mediating PI3K/Akt/eNOS signaling pathway
CW Ku, TJ Ho, CY Huang, PM Chu, HC Ou… - The American journal …, 2021 - World Scientific
A well-known medicinal mushroom in the field of traditional Chinese medicine, Cordyceps
sinensis, is a rare natural-occurring entomopathogenic fungus, and it typically grows at high …
sinensis, is a rare natural-occurring entomopathogenic fungus, and it typically grows at high …
Therapeutic actions of tea phenolic compounds against oxidative stress and inflammation as central mediators in the development and progression of health problems …
H Liu, H Guan, F He, Y Song, F Li… - Critical Reviews in …, 2023 - Taylor & Francis
Many health problems including chronic diseases are closely associated with oxidative
stress and inflammation. Tea has abundant phenolic compounds with various health …
stress and inflammation. Tea has abundant phenolic compounds with various health …
[HTML][HTML] Epigallocatechin-3-gallate plays more predominant roles than caffeine for inducing actin-crosslinking, ubiquitin/proteasome activity and glycolysis, and …
PEM Gallemit, S Yoodee, T Malaitad… - Biomedicine & …, 2021 - Elsevier
A recent expression proteomics study has reported changes in cellular proteome (set of
proteins) of human endothelial cells (ECs) induced by caffeine and epigallocatechin-3 …
proteins) of human endothelial cells (ECs) induced by caffeine and epigallocatechin-3 …