Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest
challenges facing cardiovascular medicine today. Despite being the most common form of …

With its complicated pathobiology and pathophysiology, heart failure (HF) remains an
increasingly prevalent epidemic that threatens global human health. Ferroptosis is a form of …

Finerenone is a novel non-steroidal mineralocorticoid receptor (MR) antagonist (MRA) with
high binding affinity, high MR selectivity and a short plasma half-life. In two major endpoint …

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …

Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence worldwide,
already accounting for at least half of all cases of heart failure. As most patients with HFpEF …

Obesity-related heart failure with preserved ejection fraction (HFpEF) has become a well-
recognized HFpEF subphenotype. Targeting the unfavorable cardiometabolic profile may …

Heart failure with preserved ejection fraction (HFpEF) has been recognized as the greatest
single unmet need in cardiovascular medicine. Indeed, the morbi-mortality of HFpEF is high …

BACKGROUND: Clonal hematopoiesis (CH), which results from an array of nonmalignant
driver gene mutations, can lead to altered immune cell function and chronic disease, and …

Aims Multivariable prediction models can be used to estimate risk of incident heart failure
(HF) in the general population. A systematic review and meta‐analysis was performed to …

Right ventricular–pulmonary artery coupling (RV-PA coupling) refers to the relationship
between RV contractility and RV afterload. Normal RV-PA coupling is maintained only when …