The roles of extracellular vesicles in the immune system

EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …

Context-specific regulation of extracellular vesicle biogenesis and cargo selection

AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Extracellular vesicles and nanoparticles: emerging complexities

DK Jeppesen, Q Zhang, JL Franklin, RJ Coffey - Trends in Cell Biology, 2023 - cell.com
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …

Challenges and directions in studying cell–cell communication by extracellular vesicles

G van Niel, DRF Carter, A Clayton… - … Reviews Molecular Cell …, 2022 - nature.com
Extracellular vesicles (EVs) are increasingly recognized as important mediators of
intercellular communication. They have important roles in numerous physiological and …

Therapeutically harnessing extracellular vesicles

L Cheng, AF Hill - Nature Reviews Drug Discovery, 2022 - nature.com
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

A review on exosomes application in clinical trials: perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell Communication and Signaling, 2022 - Springer
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

MicroRNA sequence codes for small extracellular vesicle release and cellular retention

R Garcia-Martin, G Wang, BB Brandão, TM Zanotto… - Nature, 2022 - nature.com
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-
cell communication in which microRNAs (miRNAs) produced and released from one cell are …