Germline stem cells (GSCs) in Drosophila are a valuable model to explore of how adult stem
cells are regulated in vivo. Genetic dissection of this system has shown that stem cell fate is …

Gametogenesis is one of the most extreme cellular differentiation processes that takes place
in Drosophila male and female germlines. This process begins at the germline stem cell …

The stem cell niches at the apex of Drosophila ovaries and testes have been viewed as
distinct in two major respects. While both contain germline stem cells, the testis niche also …

Stem cells are found in specialized microenvironments, or “niches”, which regulate stem cell
identity and behavior. The adult testis and ovary in Drosophila contain germline stem cells …

The re-use of genes in new organs forms the base of many evolutionary novelties. A well-
characterised case is the recruitment of the posterior spiracle gene network to the …

Germ-line stem cells (GSCs) are maintained by the somatic microenvironment, or GSC
niche, which ensures that GSCs can both self-renew and produce functional gametes …

Animals have evolved a fascinating array of mechanisms for conducting sexual
reproduction. These include producing the sex-specific gametes, as well as mechanisms for …

Sex determination mechanisms are thought to evolve rapidly and show little conservation
among different animal species. For example, the critical gene on the Y chromosome, SRY …

BACKGROUND Precise regulation of oogenesis is crucial to female reproduction. Seventy
percent of pests belong to lepidopteran species, so it would be interesting to explore the …

Cell‐cell signaling and adhesion are critical for establishing tissue architecture during
development and for maintaining tissue architecture and function in the adult. Defects in …