[HTML][HTML] The importance of being Casiopeina as polypharmacologycal profile (mixed chelate–copper (II) complexes and their in vitro and in vivo activities)
Z Aguilar-Jiménez, A Espinoza-Guillén… - Inorganics, 2023 - mdpi.com
In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …
[HTML][HTML] The bright and dark sides of reactive oxygen species generated by copper–peptide complexes
UK Komarnicka, MK Lesiów, M Witwicki, A Bieńko - Separations, 2022 - mdpi.com
Copper ions bind to biomolecules (eg, peptides and proteins) playing an essential role in
many biological and physiological pathways in the human body. The resulting complexes …
many biological and physiological pathways in the human body. The resulting complexes …
Liposomal form of 2-alkylthioimidazolone-based copper complexes for combined cancer therapy
TM Iakimova, AA Bubley, OP Boychenko, DA Guk… - …, 2023 - Taylor & Francis
Aim: To develop an optimized approach for encapsulating a 2-alkylthioimidazolone-based
copper coordination compound within liposomes, which could offer treatment of cancer and …
copper coordination compound within liposomes, which could offer treatment of cancer and …
[HTML][HTML] New Copper (II)-L-dipeptide-bathophenanthroline complexes as potential anticancer agents—synthesis, characterization and cytotoxicity studies—and …
Searching for new copper compounds which may be useful as antitumor drugs, a series of
new [Cu (L-dipeptide)(batho)](batho: 4, 7-diphenyl-1, 10-phenanthroline, L-dipeptide: Gly …
new [Cu (L-dipeptide)(batho)](batho: 4, 7-diphenyl-1, 10-phenanthroline, L-dipeptide: Gly …
[HTML][HTML] Development of copper complexes with diimines and dipicolinate as anticancer cytotoxic agents
Coordination complexes may act as anticancer agents. Among others, the formation of the
complex may facilitate the ligand uptake by the cell. Searching for new copper compounds …
complex may facilitate the ligand uptake by the cell. Searching for new copper compounds …
Structure elucidation, in vitro binding studies and ROS-dependent anti-cancer activity of Cu(II) and Zn(II) phthaloylglycinate(phen) complexes against MDA-MB-231 …
S Zehra, I Cirilli, S Silvestri, S Gómez-Ruiz… - Metallomics, 2021 - academic.oup.com
New mononuclear Cu (II) and Zn (II)-based complexes 1 [Cu (L) 2 (diimine) HOCH3] and 2
[Zn (L) 2 (diimine)] have been synthesized as anti-cancer chemotherapeutics targeted to …
[Zn (L) 2 (diimine)] have been synthesized as anti-cancer chemotherapeutics targeted to …
[HTML][HTML] Ternary copper complex of L-Glutamine and phenanthroline as counterions of cyclo-tetravanadate anion: Experimental–theoretical characterization and …
ND Corona-Motolinia, B Martinez-Valencia, L Noriega… - Metals, 2021 - mdpi.com
Over the last decade, therapeutic metallodrugs have become substantially effective in the
treatment of cancer. Thus, developing new effective anticancer drugs is a significant …
treatment of cancer. Thus, developing new effective anticancer drugs is a significant …
[HTML][HTML] Synthesis, crystal structure, and computational methods of vanadium and copper compounds as potential drugs for cancer treatment
ND Corona-Motolinia, B Martínez-Valencia, L Noriega… - Molecules, 2020 - mdpi.com
Transition metal-based compounds have shown promising uses as therapeutic agents.
Among their unique characteristics, these compounds are suitable for interaction with …
Among their unique characteristics, these compounds are suitable for interaction with …
Folic acid-conjugated mixed-ligand copper (II) complexes as promising cytotoxic agents for triple-negative breast cancers: A case study using MDA-MB-231 cell
S Karpagam, A Mamindla, VK Sali, RS Niranjana… - Inorganica Chimica …, 2022 - Elsevier
The new mixed-ligand copper (II) complexes [Cu (FAA)(diimine)(H 2 O)](ClO 4) 2 (1–4)[FAA
is folic acid-conjugated ethyl pyridyl amine; diimine is 1, 10-phenanthroline (phen; 1), 5, 6 …
is folic acid-conjugated ethyl pyridyl amine; diimine is 1, 10-phenanthroline (phen; 1), 5, 6 …
Highly Efficient Photoswitchable Smart Polymeric Nanovehicle for Gene and Anticancer Drug Delivery in Triple-Negative Breast Cancer
Over the past few decades, there has been significant interest in smart drug delivery systems
capable of carrying multiple drugs efficiently, particularly for treating genetic diseases such …
capable of carrying multiple drugs efficiently, particularly for treating genetic diseases such …