Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites
RM de Jong, SK Tebeje… - Immunological …, 2020 - Wiley Online Library
The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …
[HTML][HTML] Vector microbiota manipulation by host antibodies: the forgotten strategy to develop transmission-blocking vaccines
A Maitre, A Wu-Chuang, J Aželytė, V Palinauskas… - Parasites & vectors, 2022 - Springer
Human and animal pathogens that are transmitted by arthropods are a global concern,
particularly those vectored by ticks (eg Borrelia burgdorferi and tick-borne encephalitis virus) …
particularly those vectored by ticks (eg Borrelia burgdorferi and tick-borne encephalitis virus) …
[HTML][HTML] A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine
WK Tang, CH Coelho, K Miura, BCN Tentokam… - Immunity, 2023 - cell.com
Summary Pfs230 domain 1 (Pfs230D1) is an advanced malaria transmission-blocking
vaccine antigen demonstrating high functional activity in clinical trials. However, the …
vaccine antigen demonstrating high functional activity in clinical trials. However, the …
[HTML][HTML] A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle
Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the
continuous cycle of infection between the human host and the mosquito vector. Domain 1 …
continuous cycle of infection between the human host and the mosquito vector. Domain 1 …
[HTML][HTML] Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum
MC Kapulu, DF Da, K Miura, Y Li, AM Blagborough… - Scientific reports, 2015 - nature.com
Malaria transmission-blocking vaccines (TBVs) target the development of Plasmodium
parasites within the mosquito, with the aim of preventing malaria transmission from one …
parasites within the mosquito, with the aim of preventing malaria transmission from one …
Functional comparison of Plasmodium falciparum transmission-blocking vaccine candidates by the standard membrane-feeding assay
K Miura, E Takashima, B Deng, G Tullo… - Infection and …, 2013 - Am Soc Microbiol
Recently, there has been a renewed interest in the development of transmission-blocking
vaccines (TBV) against Plasmodium falciparum malaria. While several candidate TBVs have …
vaccines (TBV) against Plasmodium falciparum malaria. While several candidate TBVs have …
Nanovaccines for malaria using Plasmodium falciparum antigen Pfs25 attached gold nanoparticles
Malaria transmission-blocking vaccines (TBV) targeting sexual stages of the parasite
represent an ideal intervention to reduce the burden of the disease and eventual elimination …
represent an ideal intervention to reduce the burden of the disease and eventual elimination …
[HTML][HTML] Structural and immunological characterization of recombinant 6-cysteine domains of the Plasmodium falciparum sexual stage protein Pfs230
NJ MacDonald, V Nguyen, R Shimp, K Reiter… - Journal of Biological …, 2016 - ASBMB
Development of a Plasmodium falciparum (Pf) transmission blocking vaccine (TBV) has the
potential to significantly impact malaria control. Antibodies elicited against sexual stage …
potential to significantly impact malaria control. Antibodies elicited against sexual stage …
[HTML][HTML] Anti-microbiota vaccine reduces avian malaria infection within mosquito vectors
J Aželytė, A Wu-Chuang, R Žiegytė… - Frontiers in …, 2022 - frontiersin.org
Animal and human pathogens that are transmitted by arthropods are a global concern,
particularly those vectored by mosquitoes (eg, Plasmodium spp. and dengue virus). Vector …
particularly those vectored by mosquitoes (eg, Plasmodium spp. and dengue virus). Vector …
[HTML][HTML] Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum
The Plasmodium falciparum Pf s230 and Pf s48/45 proteins are expressed during
transmission from man to mosquito and are leading candidates for a malaria transmission …
transmission from man to mosquito and are leading candidates for a malaria transmission …