Flavonoids in cancer and apoptosis
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …
approaches to cancer treatment, they are often painful due to adverse side effects and are …
A recent review of citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production
Background Metabolic syndromes are the multi-metabolic abnormality characterized by
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …
Organometallic gold (III) complexes similar to tetrahydroisoquinoline induce ER-stress-mediated apoptosis and pro-death autophagy in A549 cancer cells
KB Huang, FY Wang, XM Tang, HW Feng… - Journal of medicinal …, 2018 - ACS Publications
Agents inducing both apoptosis and autophagic death can be effective chemotherapeutic
drugs. In our present work, we synthesized two organometallic gold (III) complexes …
drugs. In our present work, we synthesized two organometallic gold (III) complexes …
Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53
Necrosis, unregulated cell death, is characterized by plasma membrane rupture as well as
nuclear and cellular swelling. However, it has recently been reported that necrosis is a …
nuclear and cellular swelling. However, it has recently been reported that necrosis is a …
Pharmacological properties and therapeutic potential of naringenin: a citrus flavonoid of pharmaceutical promise
N Rani, S Bharti, B Krishnamurthy… - Current …, 2016 - ingentaconnect.com
Naringenin chemically known as 5, 7-dihydroxy-2-(4-hydroxyphenyl) chroman-4-one is a
common dietary polyphenolic constituent of the citrus fruits. It has received considerable …
common dietary polyphenolic constituent of the citrus fruits. It has received considerable …
BH3-only protein BIM: an emerging target in chemotherapy
BH3-only proteins constitute major proportion of pro-apoptotic members of B-cell lymphoma
2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development …
2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development …
[HTML][HTML] Mitochondria-targeted platinum (II) complexes induce apoptosis-dependent autophagic cell death mediated by ER-stress in A549 cancer cells
FY Wang, XM Tang, X Wang, KB Huang… - European Journal of …, 2018 - Elsevier
Agents with multiple modes of tumor cell death can be effective chemotherapeutic drugs.
One example of a bimodal chemotherapeutic approach is an agent that can induce both …
One example of a bimodal chemotherapeutic approach is an agent that can induce both …
Effect of crocin and naringenin supplementation in cryopreservation medium on post-thaw rooster sperm quality and expression of apoptosis associated genes
The aim of our study was to examine the effects of crocin (0.5 (C0. 5), 1 (C1) and 1.5 (C1. 5)
mM) and naringenin (50 (N50), 100 (N100) and 150 (N150) μM) in cryopreservation …
mM) and naringenin (50 (N50), 100 (N100) and 150 (N150) μM) in cryopreservation …
Flavonoids modulate tight junction barrier functions in hyperglycemic human intestinal Caco-2 cells
Objectives: Diabetes mellitus is a chronic disease requiring lifelong medical attention. With
hundreds of millions suffering worldwide and a rapidly rising incidence, diabetes mellitus …
hundreds of millions suffering worldwide and a rapidly rising incidence, diabetes mellitus …
[HTML][HTML] Naringenin accords hepatoprotection from streptozotocin induced diabetes in vivo by modulating mitochondrial dysfunction and apoptotic signaling cascade
R Kapoor, P Kakkar - Toxicology reports, 2014 - Elsevier
Diabetic complications cause noticeable liver damage, which finally progresses to diabetic
hepatopathy. Nutritive antioxidants not only reduce the liver damage, but also prevent it by …
hepatopathy. Nutritive antioxidants not only reduce the liver damage, but also prevent it by …